program｜The 93rd Annual Meeting of the Japanese Pharmacological Society

Late-Breaking Session

1-LBS-0313:1014:10 Role of astrocytic histamine N-methyltransferase in brain functions Yuna Takahashi, Takeo Yoshikawa, Rina Otsuka, Kazuhiko Yanai Dept. Pharmarcol., Tohoku Univ. Grad. Sch. Med.

1-LBS-0413:1014:10 The development of novel anti-depressant targeting AMPA receptor Hara Megumi Yokohamacity university

1-LBS-0513:1014:10 QPRT Deficit Leads Motor and Cognitive Dysfunction through Increase of Oxidative Stress in the Dopaminergic Neuronal System by Quinolinic Acid Akihiro Mouri¹, Moe Niijima¹, Tomoaki Teshigawara², Kazuo Kunisawa¹, Hisayoshi Kubota¹, Yasuko Yamamoto², Kuniaki Saito², Toshitaka Nabeshima³ ¹Department of Regulatory Science for Evaluation & Development of Pharmaceuticals & Devices, Fujita Health University Graduate School of Health Science, ²Department of Disease Control and Prevention, Fujita Health University Graduate School of Health Science, ³Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Science

1-LBS-0613:1014:10 Oxytocin recovers Aβ-induced impairment of hippocampal synaptic plasticity in mice Takahshi Junpei¹, Daisuke Yamada¹, Yudai Ueta¹, Takashi Iwai², Eri Koga¹, Mitsuo Tanabe², Jun-Ichiro Oka¹, Akiyoshi Saitoh¹ ¹Lab Pharmacol, Fac Pharm Sci, Tokyo Univ of Science., ²Lab Pharmacol, Fac Pharm , Kitasato Univ

1-LBS-0713:1014:10 NOX1/NADPH in the hypothalamus regulate anxiety-like behaviors in mice Masakazu Ibi, Xueqing Zhang, Chihiro Yabe-Nishimura Kyoto Prefectural University of Medicine

1-LBS-0813:1014:10 New animal behavioral pharmacology using wireless power supply and implantable sensors Kazuhiko Yanai¹, Takeo Yoshikawa¹, Kenichi Sagara², Shu Sasaki² ¹Tohoku Univ. Sch. Med. Dept. Pharmacol., ²HIKARIDENSHI, CO., LTD

1-LBS-0913:1014:10 Effect of the herbicide glufosinate-ammonium exposure on central nervous system Hironori Izumi¹, Maina Demura¹, Ayako Imai¹, Tomoyuki Yoshida¹, Ryohei Ogawa², Hisashi Mori¹ ¹Dept. of Mol. Neurosci., Grad. Sch. of Med. & Pharmaceut. Sci., Univ. of Toyama, ²Dept. Radiol., Grad. Sch. Med. & Pharmaceut. Sci., Univ. of Toyama

1-LBS-1013:1014:10 Novel Reporter System Monitoring IL-18 Specific Signaling can be Applied to High-Throughput Screening Yonezawa Tomo¹, Kurata Riho², Xiaofeng Cui³, Masamitsu Harada¹, Jun Nagai¹, Ysuhiro Yoshida⁴ ¹Center for Therapeutic Innovation, Gene Research Center for Fronties Life Sciences, Nagasaki University, Graduate School of Biomedical Sciences, ²Education and Research Center For Fundamental Pharmaceutical Sciences, Osaka University of Pharmaceutical Sciences, ³School of Chemistry, Chemical Engineering and Life Sciences, School of Materials and Engineering, Wuhan University of Technology, ⁴Department of Immunology and Parasitology, University of Occupational and Environmental Health

1-LBS-1113:1014:10 Ca²⁺-sensing receptor-G_q/11 protein signaling pathway is involved in nitric oxide release from human vascular endothelial cells Takahiro Horinouchi, Yuichi Mazaki, Soichi Miwa Dept. Cell. Pharmacol., Grad. Sch. Med., Hokkaido Univ. Sapporo 060-8638, Japan.

1-LBS-1213:1014:10 Pimaric acid inhibits contraction of pulmonary artery via BKCa channel activation Ishida Masashi, Yoshiaki Suzuki, Hisao Yamamura Dept. Mol. Cell. Pharmacol., Grad. Sch. Pharmaceut. Sci., Nagoya City Univ.

1-LBS-1313:1014:10 Inhibitory effect of melatonin on voltage-dependent potassium (Kv4.2) channels Mishima Hiroki, Yoshiaki Suzuki, Hisao Yamamura Dept. Mol. Cell. Pharmacol., Grad. Sch. Pharmaceut. Sci., Nagoya City Univ.

1-LBS-1413:1014:10 Adverse Outcome Pathway (AOP) development on Wnt/beta-catenin signaling pathway related to cancer Shihori Tanabe¹, Kazuhiko Aoyagi², Sabina Quader³, Horacio Cabral⁴, Ryuichi Ono⁵, Akihiko Hirose¹, Hiroshi Yokozaki⁶, Hiroki Sasaki⁷ ¹Div. Risk Assessment, Biol. Safety Res. Center, Natl. Inst. Health Sci., ²Dept. Clin. Genomics, Natl. Cancer Center Res. Inst., ³iCONM, ⁴Grad. Sch. Engineer., Tokyo Univ., ⁵Div. Cel. Mol. Toxicol., Biol. Safety Res. Center, Natl. Inst. Health Sci., ⁶Dept. Pathol., Grad. Sch. Med., Kobe Univ., ⁷Dept. Transl. Oncol., Natl. Cancer Center Res. Inst.

1-LBS-1513:1014:10 Early postnatal lethality of mice lacking mitochondrial protein p13 Norihito Shintani, Hiroki Ueno, Satomi Hara, Sae Ogura, Naoki Inoue, Yohei Morota, Hitoshi Hashimoto Grad. Sch. Pharmaceut. Sci., Osaka Univ.

1-LBS-1613:1014:10 Effects of different sweetener charge-methods on blood glucose level and insulin concentration of mice Sachiko Sato, Yukiko Kondo, Eiichi Taira Dept. of Pharmacol., Iwate Med. Univ., Morioka, Japan

1-LBS-1713:1014:10 Age-dependent change in size distribution of plasma sEV from Wistar rat Yusei Fujioka, Kosuke Otani, Muneyoshi Okada, Hideyuki Yamawaki Lab. Vet. Pharmacol., Sch. Vet. Med., Kitasato Univ.

1-LBS-1813:1014:10 Pharmacological profile of fingolimod for pulmonary arterial hypertension Moe Fujiwara¹, Aya Yamamura², Yoshiaki Suzuki¹, Hisao Yamamura¹ ¹Dept. Mol. Cell. Pharmacol., Grad. Sch. Pharmaceut. Sci., Nagoya City Univ., ²Dept. Physiol., Aichi Med. Univ.

1-LBS-1913:1014:10 BK_Ca channel inhibition decreases the proliferation of human hepatic stellate cells Kondo Rubii, Yoshiaki Suzuki, Hisao Yamamura Dept. Mol. & Cell. Pharmacol., Grad. Sch. Pharmaceut., Nagoya City Univ.