program｜The 93rd Annual Meeting of the Japanese Pharmacological Society

Symposium3

The current situation in genomic medicine and peptide drug discovery and their applications to unmet needs in the field of cardiovascular health

1-S03-19:0010:30 Trans-layer omics analysis, disease biology, and drug discovery Yukinori Okada Dept. Stat Genet, Grad. Scho. Med., Osaka Univ.

1-S03-29:0010:30 Revolutionary therapeutic peptides Hiroaki Suga Dept. Chem., Grad. Sch. Sci. Univ. Tokyo

1-S03-39:0010:30 Sterile inflammation and inflammasome in cardiovascular medicine: current status and prospects of therapy Masafumi Takahashi Div. Inflammation Research, Jichi Medical University

Symposium10

Frontier in drug discovery targeting nucleic acids

1-S10-110:3012:00 Drug Discovery for Genetic Diseases Caused by Aberrant mRNA Splicing Masatoshi Hagiwara Dept. Anat. & Dev. Biol., Grad. Sch. Med., Kyoto Univ.

1-S10-210:3012:00 Regulation of higher order structures and function of RNA by RNA-binding small molecules Kazuhiko Nakatani ISIR, Osaka Univ.

1-S10-310:3012:00 Pyrrole-Imidazole Polyamides as artificial genetic switches Hiroshi Sugiyama Dept. Chem., Grad. Sch. Sci., Kyoto Univ.

1-S10-410:3012:00 From the structure analysis of RNA to the identification of novel drug targets Gota Kawai Dept. Life Science, Chiba Inst. Tech.

Oral Sessions

1-O-00114:1514:27 Search of itch-producing substance(s) released from skin cells of atopic dermatitis model mice Masanori Fujii, Masayuki Nakashima, Chihiro Sakurai, Satoshi Tanaka Dept. Pharmacol., Kyoto Pharm. Univ.

1-O-00214:2714:39 Type 1 regulatory T (Tr1) cells increased by sublingual immunotherapy (SLIT) suppressed allergic inflammation Masaya Matsuda¹, Tetsuya Terada², Miki Inaba¹, Junpei Hamaguchi¹, Naoki Takemoto¹, Kazuyuki Kitatani¹, Ryo Kawata², Takeshi Nabe¹ ¹Lab. of Immunopharmacol., Fac. of Pharm. Sci., Setsunan Univ., ²Dept. Otorhinolaryngol. Head & Neck Surg., Osaka Med. Col.

1-O-00314:3914:51 Thromboxane A₂ is involve in the skin inflammation in mice with atopy-like dermatitis Tsugunobu Andoh, Yuki Ando, Daisuke Uta, Toshiaki Kume Dept. Applied Pharmacol., Sch. Med. Pharm. Sci., Univ. Toyama

1-O-00414:5115:03 Establishment of a novel anti-CD20 monoclonal antibody C₂₀Mab-11 using the Cell-Based Immunization and Screening (CBIS) method for the detection of B cells in many applications Yoshikazu Furusawa^1,2,3, Mika K. Kaneko¹, Takashi Miwa³, Masato Fukui³, Yukinari Kato^1,2 ¹Dept. Antibody Drug Development, Grad. Sch. Med., Tohoku Univ., ²New Industry Creation Hatchery Center., Tohoku Univ., ³ZENOAQ RESOURCE CO., LTD.

1-O-00515:0315:15 Mechanism of action of pyrogallol on calcineurin-NFAT signaling Hiroyuki Mizuguchi¹, Tomohiro Nakano², Kouhei Nishida², Tomohiro Ito², Tomoharu Wakugawa², Osamu Kaminuma³, Noriko Kitamura⁴, Tatsuya Ishida⁵, Masami Yabumoto⁶, Yoshiaki Kitamura⁷, Noriaki Takeda⁷, Hiroyuki Fukui^6,7 ¹Lab. Pharmacol. Facul. Pharm., Osaka Ohtani Univ., ²Dept. Mol. Pharmacol., Inst. Biomed. Sci. Tokushima Univ. Grad. Sch., ³Dept. Disease. Model., Res. Inst. Rad. Biol. Med. Hiroshima Univ., ⁴Allergy Immunol. Proj. Tokyo Metropol. Inst. Med. Sci., ⁵Food Microbial. Func.Res. Lab., R & D Div. Meiji Co., Ltd., ⁶Med. Corp. Kinshukai, ⁷Dept. Otolaryngol., Inst. Biomed. Sci. Tokushima Univ. Grad. Sch.

YIA

1-YIA-0715:2015:32 Deficiency of cardiac natriuretic peptide signaling promotes peripartum cardiomyopathy-like remodeling in the mouse heart Takeshi Tokudome¹, Kentaro Otani², Chizuko Kamiya³, Mikiya Miyazato¹, Kenji Kangawa⁴ ¹Dept. Biochemistry., NCVC, ²Dept. Regenerative Medicine-Tissue Engineering., NCVC, ³Div. Perinatology-Gynecology., NCVC, ⁴NCVC

1-YIA-0815:3215:44 2,5-Dimethylcelecoxib attenuates cardiac fibrosis after cryoinjury-induced myocardial infarction by suppressing the fibroblast-myofibroblast differentiation Eigo Ikushima¹, Shin Ishikane¹, Tomohiro Takiguchi², Yumiko Toyohira¹, Fumi Takahashi¹ ¹Department of Pharmacology, University of Occupational and Environmental Health, Japan, ²Dep. Clin. Pharm., Grad. Sch. Med., Kyushu Univ.

1-YIA-0915:4415:56 Physiological role of gp130 receptor in newborn mouse cardiomyocyte development Hiroyuki Kawagishi^1,2, Tsutomu Nakada³, Takuro Numaga-Tomita¹, Mitsuhiko Yamada¹ ¹Dept. of Mol. Pharm., Shinshu Univ. Sch. of Med., ²Dept. of Biotech., Institute for Biomedical Sci., Shinshu Univ., ³Dept. of Instrumental Analysis, Res. Ctr. for Supports to Advanced Sci., Shinshu Univ.

1-YIA-1116:0816:20 Therapeutic silencing of centromere protein X ameliorates hyperglycemia in zebra fish and mouse models of type 2 diabetes mellitus Zang Liqing¹, Yasuhito Shimada², Hiroko Nakayama¹, Norihiro Nishimura¹ ¹Graduate School of Regional Innovation Studies, Mie University, ²Department of Integrative Pharmacology, Mie University Graduate School of Medicine

1-YIA-1216:2016:32 SMTP-44D improves diabetic neuropathy in mice Ryosuke Shinouchi^1,2, Keita Shibata^1,2, Shiori Jono^1,2, Terumasa Hashimoto^1,2, Keiji Hasumi³, Koji Nobe^1,2 ¹Div. Pharmacol., Dept. Pharmacol. Toxicol. Ther., Showa Univ. Sch. Pharmacy., ²Pharmacol. Res. Center., Showa Univ., ³Dept. Appl. Biol. Sci., Tokyo Univ. of Agricul. and Technol.