program｜The 93rd Annual Meeting of the Japanese Pharmacological Society

Symposium1

Molecular basis of neuron-neuron and neuron-non neuronal cell communication in health and disease

1-S01-19:0010:30 Regulation of anterograde transcytosis of neurotrophin receptors and its role in health and diseases Naoya Yamashita Dept. of Cell and Mol Pharmacol., Juntendo Univ., Sch. Med.

1-S01-29:0010:30 Neuronal Signaling in Islet Development and Function Rejji Kuruvilla Department of Biology, Johns Hopkins University

1-S01-39:0010:30 InSyn1 regulates GABAergic inhibition via the dystroglycan complex and is required for cognitive behaviors in mice Akiyoshi Uezu^1,2, Erin Hisey², Yoshihiko Kobayashi², Yudong Gao², Tyler Bradshaw³, Patrick Devlin², Ramona Rodriguiz⁴, Purushothama Tata², Scott Soderling^1,2,3 ¹CASTAG BIOSCIENCES INC., ²The Departments of Cell Biology, Duke University Medical School, ³The Departments of Neurobiology, Duke University Medical School, ⁴Psychiatry and Behavioral Sciences and Mouse Behavioral and Neuroendocrine Analysis Core Facility, Duke University Medical School

1-S01-49:0010:30 Chemico-genetic discovery of molecules underlying tripartite-synaptic function in vivo Tetsuya Takano Department of Cell Biology, Duke University Medical School

Symposium8

Cutting-edge of neural circuit research by pharmacology and optogenetics

1-S08-110:3012:00 Projection-identified large-scale recording reveals pathway-specific information outflow from the subiculum Takuma Kitanishi^1,2 ¹Dept. Physiol., Osaka City Univ. Grad. Sch. Med., ²PRESTO, JST

1-S08-210:3012:00 A novel ligand selectively visualizes and activates chemogenetic receptors in non-human primates Yuji Nagai Dept. Functional Brain Imaging, NIRS, QST

1-S08-310:3012:00 Novel optogenetic and chemogenetic tools for understanding of molecular mechanisms which underlie learning and memory. Wataru Kakegaea, Michisuke Yuzaki Dept. Physiol., Keio Univ. Sch. of Med.

1-S08-410:3012:00 CRMP2 Binding Compound Accelerates Recovery from Central Nervous System damage Jitsuki Susumu, Takuya Takahashi Dept. Physiol., Yokohama City Univ. Grad. Sch. of Med.

Symposium15

New insight of physiological functions via GPCRs

1-S15-114:2015:50 GPCRs for ketone bodies and energy homeostasis Junki Miyamoto^1,2 ¹Tokyo University of Agriculture and Technology, ²AMED-CREST

1-S15-214:2015:50 Physiological functions of GPCRs sensing Long-chain Free Fatty Acids Atsuhiko Ichimura Dept. BioChem., Grad Sch Pharm Sci., Kyoto Univ.

1-S15-314:2015:50 Regulation of physiological lipid homeostasis by prostaglandin receptor Tomoaki Inazumi, Yukihiko Sugimoto Grad. Sch. Pharmaceut. Sci., Kumamoto Univ.

1-S15-414:2015:50 V1b vasopressin receptor accelerates interaction between β-arrestin and μ-type opioid receptor and enhances opioid tolerance and adenylate cyclase sensitization Taka-Aki Koshimizu¹, Kenji Honda², Yukio Takano² ¹Div. Mol. Pharm. Jichi Med. Univ., ²Dept. Physiol. Pharm., Pharmaceut. Sci., Fukuoka Univ.

Student Sessions

central nervous system (CNS) (1)

Chair：Takayo Odaira（Dept. Pharmacol., Tohoku Med. & Pharmaceut. Univ.）

Chair：Wataru Matsuura（Dept. Clinical Pharm. , Fac. Pharmaceut. Sci., Kobe Gakuin Univ.）

1-SS-0016:4817:00 Establishment of chronic postsurgical pain model and analysis of its therapeutic target Kenichi Tanaka¹, Yoshiyuki Yamabe¹, Takashige Kondo¹, Misa Matsufuji¹, Michiko Narita², Yusuke Hamada¹, Daisuke Sato¹, Yosuke Katsuda³, Masako Iseki³, Takahiro Ochiya², Naoko Kuzumaki¹, Minoru Narita^1,3 ¹Dept. Pharmacol., Hoshi Univ., ²Institute of Medical Science, Tokyo Medical., Univ., ³Dept. Anesthesiol., Pain Med., Juntendo Univ.

1-SS-0117:0017:12 Involvement of supraspinal orexin-A/orexin receptors in the regulation of central post-stroke pain Wataru Matsuura, Shogo Tokuyama Dept. Clinic. Pharm., Sch. Pharmaceu. Sci., Kobegakuin Univ.

1-SS-0217:1217:24 Identification of a binding protein for 2ccPA and characterization of its roles in microglial cell death Sahara Yasuka¹, Toshifumi Sakai¹, Tamotsu Tsukahara² ¹Dept. Pharmcol.Therap. Innov., Sch. Pharmaceu. Sci., Nagasaki Uni, ²Dept. Pharmcol.Therap. Innov., Grad. Sch. Biomed. Sci., Nagasaki Uni

1-SS-0317:2417:36 Type 1 metabotropic glutamate receptor 1 and GABA B receptor form complexes at cell membrane and mutually modulate their function Hakushun Sakairi¹, Yuji Kamikubo², Toshihide Tabata³, Takashi Sakurai¹ ¹Department of Pharmacology, Juntendo University Graduate School of Medicine, Japan, ²Department of Pharmacology, Juntendo University School of Medicine, Japan, ³Laboratory for Biological Information Processing, Graduate School of Science and Engineering, University of Toyama, Japan

1-SS-0417:3617:48 Characterization of direction-specific vagus nerve spikes in a freely moving rodent Toya Okonogi¹, Yu Shikano^1,2, Yuya Nishimura¹, Akihiro Yamanaka³, Yuji Ikegaya¹, Takuya Sasaki^1,4 ¹Lab. Chem. Pharmacol., Grad. Sch. Pharmaceut. Sci., Univ. Tokyo, ²Dept. Neuropsychiatry., Keio Univ. Sch. Med., ³Dept. Neurosci. II., Res. Inst. Environ. Med., Nagoya Univ., ⁴JST PRESTO

1-SS-0517:4818:00 OX2R-selective orexin agonism is sufficient to ameliorate narcoleptic symptoms, cataplexy and sleep/wakefulness fragmentation in mouse models Yamamoto Hikari, Yoko Irukayama, Yukiko Ishikawa, Yukiko Namekawa, Tsuyoshi Nemoto, Hiromu Tanaka, Genki Takahashi, Masashi Yanagisawa International Institute for Integrative Sleep Medicine (WPI-IIIS), Tsukuba Univ.

Student Sessions

mental disorder, neurodevelopment

Chair：Takaaki Aratake（Dept. Pharmacol., Sch. Med., Kochi Univ.）

Chair：Kazuya Matsuo（Dept. Pharmacol., Grad. Sch. Pharm. Sci. & Fac. Pharm. Sci., Tohoku Univ.）

1-SS-3218:0018:12 Relationship between brain oxidative stress and autistic behaviors in autism spectrum disorder rats Kazuya Matsuo, Yasuharu Shinoda, Kohji Fukunaga Dept. Pharmacol., Grad. Sch. Pharm. Sci., Tohoku Univ.

1-SS-3318:1218:24 The cognitive function of the mice with an exonic deletion of RELN is impaired in touchscreen-based visual discrimination task Geyao Dong¹, Taku Nagai¹, Jingzhu Liao¹, Daisuke Mori², Bolati Wulaer¹, Toshitaka Nabeshima^3,4, Norio Ozaki², Kiyofumi Yamada¹ ¹Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, ²Department of Psychiatry, Nagoya University Graduate School of Medicine, ³Advanced Diagnostic System Research Laboratory Fujita Health University, Graduate School of Health Sciences, ⁴Aino University

1-SS-3418:2418:36 Effect of new preventive medicine on pentylenetetrazol-induced kindled mice using database analyses Shimon Takahashi^1,2, Kenshi Takechi³, Natsumi Jozukuri², Masayuki Chuma³, Mitsuhiro Goda^1,2, Yuya Horinouchi⁵, Yoshito Zamami^1,2, Yuki Ishizawa‐Izawa⁴, Yasumasa Ikeda⁵, Keisuke Ishizawa^1,2 ¹Dept. Pharm., TokushimaUniv. Hosp., ²Dept. Clin. Pharmacol. Ther., Grad. Sch. Biomed. Sci., Tokushima Univ., ³Clin. Trial Ctr. Developmental Therap.,Tokushima Univ. Hosp., ⁴AWA Support Ctr, Tokushima Univ., ⁵Dept. Pharmacol., Grad. Sch. Biomed. Sci., Tokushima Univ.

1-SS-3518:3618:48 Alzheimer's drug candidate, SAK3 enhances the proteasome activity and inhibits amyloid aggregation in Alzheimer‘s disease brain Hisanao Izumi, Kohji Fukunaga Dept. Pharmcol., Grad. Sch. Pharmaceu. Sci., Tohoku Univ.

1-SS-3618:4819:00 Neuroinflammation aggravates spreading alpha-synuclein oligomerization in Lewy body dementia mice Yamada Ryo, Jing Xu, Mako Fukunaga, Kohji Fukunaga Dept. Pharmacol., Grad. Sch. Pharmaceu. Sci., Tohoku Univ.