program｜The 93rd Annual Meeting of the Japanese Pharmacological Society

Symposium6

Neuroprotection mediated by promoting glutathione synthesis in the central nervous system

1-S06-19:0010:30 Neuroprotective properties of the excitatory amino acid carrier 1 (EAAC1). Koji Aoyama Dept. Pharmacol.,Sch. Med. Teikyo Univ.

1-S06-29:0010:30 The involvement of EAAC1 in diurnal variation of ischemic Zn²⁺ toxicity Youichirou Higashi¹, Takaaki Aratake^1,2, Shogo Shimizu¹, Takahiro Shimizu¹, Motoaki Saito¹ ¹Dept. Pharmacol., Kochi Med. Sch., Kochi Univ., ²JSPS Research Fellow

1-S06-39:0010:30 EAAC1 gene deletion reduces adult hippocampal neurogenesis after transient cerebral ischemia Bo Young Choi¹, Min Sohn², Sang Won Suh¹ ¹Department of Physiology, Hallym University, College of Medicine, ²Department of Nursing, Inha University

1-S06-49:0010:30 Glutathione in astrocytes as a target of neuroprotection Masato Asanuma, Ikuko Miyazaki Dept. of Medical Neurobiology, Okayama Univ. Grad. Sch. of Med., Dent. and Pharmaceut. Sci.

Symposium13

Neuropharmacology of super-rare diseases in the CNS

1-S13-110:3012:00 Novel therapeutic approach mediated by microglia for rare brain diseases Takeshi Ikeuchi Dept. Mol. Genet., Brain Res. Inst., Niigata Univ.

1-S13-210:3012:00 Glial cells and pharmacological targets in Sandhoff disease Yasuhiro Ogawa¹, Hitoshi Sakuraba², Kazuhiko Oishi¹ ¹Dept. Pharmacol., Meiji Pharmaceutical University, ²Dept. Clin. Genet., Meiji Pharmaceutical University

1-S13-310:3012:00 Pathological role of astrocytes in neurodegeneration of multiple sclerosis Mika Takarada-Iemata, Thuong Manh Le, Nahoko Okitani, Osamu Hori Dept. Neuroanat., Grad. Sch. Med. Sci., Kanazawa Univ.

1-S13-410:3012:00 Research on the molecular pathogenesis of "primary astrocyte disorder" Alexander disease. Kozo Saito, Eiji Shigetomi, Schuichi Koizumi Dept. Neuropharmacol., Interdiscipl. Grad. Sch. Med., Univ. Yamanashi

YIA

1-YIA-0114:1014:22 Chronic histamine decrease in adult mice induced depression-like behavior and impaired sleep-wake cycle Yo Yamada¹, Takeo Yoshikawa¹, Fumito Naganuma^1,2, Kazuhiko Yanai¹ ¹Dept.Pharmacol.,Grad.Sch.Med.,Tohoku Univ., ²Div. Pharmacol., Tohoku Med Pharm Univ.

1-YIA-0214:2214:34 Chronic pain-induced plastic change in the extended amygdala neural circuit causes maladaptive anxiety Naoki Yamauchi, Hiroshi Nomura, Taiju Amano, Masabumi Minami Dept. of Pharmacol., Grad. Sch. of Pharmaceut. Sci., Hokkaido Univ.

1-YIA-0314:3414:46 Analysis of ultrastructural alterations in the mouse medial prefrontal cortex toward the understanding of pathophysiology of social stress-induced depressive-like behaviors Hirotaka Nagai, Tomoyuki Furuyashiki Div. Pharmacol., Grad. Sch. Med., Kobe Univ.

1-YIA-0414:4614:58 KNT-127, a selective delta-opioid receptor agonist, exhibits antidepressant effects through PI3K-Akt-mTOR signal transduction in the mice prefrontal cortex. Yoshioka Toshinori¹, Daisuke Yamada¹, Keita Iio², Hiroshi Nagase², Akiyoshi Saitoh¹ ¹Lab Pharmacol, Fac Pharm Sci, Tokyo Univ of Science, Chiba, Japan., ²IIIS, Univ of Tsukuba, Ibaraki, Japan.

1-YIA-0514:5815:10 Roles and mechanisms of social defeat stress-induced prostaglandin E₂ synthesis in the mouse brain Xiang Nie, Shiho Kitaoka, Tomoyuki Furuyashiki Div. Pharmacol., Grad. Sch. Med., Kobe Univ.

1-YIA-0615:1015:22 8-Hydroxylation and glucuronidation of mirtazapine in Japanese psychiatric patients: Significance of the glucuronidation pathway of 8-hydroxy-mirtazapine. Masataka Shinozaki¹, Jason Pierce^1,3,4, Yuki Hayashi¹, Takashi Watanabe¹, Taro Sasaki¹, Hazuki Komahashi-Sasaki¹, Kazufumi Akiyama², Kazuko Kato⁵, Yoshimasa Inoue¹, Shoko Tsuchimine^6,7, Norio Yasui-Furukori^1,7, Yuji Ozeki^1,8, Kazutaka Shimoda¹ ¹Dept. Psychiatry., Dokkyo Med Univ., ²Dept. Biological Psychiatry and Neuroscience., Dokkyo Med Univ., ³Virginia Mason Med. Center., ⁴Med. Univ. of South Carolina., ⁵Sakura La Mental Clinic., ⁶National Center of Neurology and Psychiatry., ⁷Dept. Neuropsychiatry., Hirosaki Univ Grad Sch. Med., ⁸Dept. Psychiatry., Shiga Univ. Med. Science.

YIA

1-YIA-2415:2215:34 Establishment of a new method for long-term single-molecule fluorescence imaging and its application to synaptic molecules Shinkuro Kobayashi, Yohei Okubo, Shigeyuki Namiki, Daisuke Asanuma, Kenzo Hirose Dept. Pharm., Grad. Sch. Med., the Univ. of Tokyo

1-YIA-2515:3415:46 Auxin-mediated rapid degradation of target proteins in neurons Risako Nakano¹, Naoki Ihara¹, Shota Morikawa¹, Ai Nakashima¹, Masato Kanemaki^2,3, Yuji Ikegaya¹, Haruki Takeuchi¹ ¹Lab. Chem. Pharmacol., Grad. Sch. Pharmaceut. Sci., Univ. Tokyo, ²Mol. Cell Eng. Lab., National Inst. Genet., ROIS, ³Dept. Genet., Grad. Univ. Adv. Studies

1-YIA-2615:4615:58 Phosphorylation of Npas4 by MAPK regulates reward-related gene expression and behaviors Yasuhiro Funahashi¹, Anthony Ariza¹, Ryosuke Emi¹, Yifan Xu¹, Shan Wei², Sachi Kozawa¹, Rijwan Uddin Ahammad¹, Mengya Wu¹, Tetsuya Takano¹, Yoshimitsu Yura¹, Keisuke Kuroda¹, Taku Nagai², Mutsuki Amano¹, Kiyofumi Yamada², Kozo Kaibuchi^1,3 ¹Department of Cell Pharmacology, Nagoya University Graduate School of Medicine, ²Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, ³Institute for Comprehensive Medical Science, Fujita Health University

1-YIA-2715:5816:10 In vivo whole-cell recordings from amygdalar neurons Yu Sato, Yuji Ikegaya Lab. Chem. Pharmacol., Grad. Sch. Pharmaceut. Sci., Univ. Tokyo

1-YIA-2816:1016:22 Optogenetic recording and manipulation of median raphe serotonin neurons in reward-related behavior. Hiroyuki Kawai, Yuma Nagai, Masashi Koda, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kaneko Dept. Mol. Pharmacol., Grad. Sch. Pharmaceut. Sci., Kyoto Univ.

1-YIA-2916:2216:34 Neural mechanisms underlying regulation of motivation for voluntary wheel running in mice Yusaku Futami, Tong Zhang, Kazuhei Niitani, Kazuya Tokumura, Hitoki Sasase, Hirohito Esaki, Satoshi Deyama, Katsuyuki Kaneda Lab. Mol. Pharmacol., Inst. Med., Pharmaceut., Health Sci., Kanazawa Univ