program｜The 94th Annual Meeting of the Japanese Pharmacological Society

Symposium5

Cutting-edge research of male urogenital disorders pioneered by young academic researchers

1-S05-19:0010:30 Pathophysiology and pharmacotherapy of benign prostatic disorders Naoki Aizawa Dept. Pharmacol. Toxicol., Dokkyo Medical Univ.

1-S05-29:0010:30 A Novel Approach to Treating Erectile Dysfunction with a Light-Controlled Nitric Oxide Donor Yuji Hotta¹, Kazunori Kimura^1,2 ¹Nagoya City Univ. Grad. Sch. Pharmaceut. Sci. Dept. Hosp. Pharm., ²Nagoya City Univ. Grad. Sch. Med. Sci. Dept. Clin. Pharmceutics.

1-S05-39:0010:30 Pharmacological analysis of the regulatory mechanisms of sperm hyperactivation by ouabain Gen L. Takei Dept. Pharmacol. Toxicol. Dokkyo Med. Univ.

1-S05-49:0010:30 Reconstruction of spemartogonial stem cell niche for spermatogenic failure and human testis reconstitution in mouse Yokonishi Tetsuhiro Kawasaki Medical University, Department of Anatomy

Company-Organized Symposium

Forefront of development of therapeutic agents for renal diseases

1-S11-110:3012:00 Challenges in drug discovery research and the effects of SGLT2 inhibitor against diabetic kidney disease Naoki Kojima Taisho Pharmaceut. Discovery Lab. Pharmacol. 2

1-S11-210:3012:00 Challenges in diabetic kidney disease: therapeutic potential of bardoxolone methyl Kengo Yamawaki Kyowa Kirin Co.,Ltd. Nephrology R&D Unit, R&D Division

1-S11-310:3012:00 Tolvaptan, a vasopressin V₂ receptor antagonist, is the world’s first approved drug for treatment of autosomal dominant polycystic kidney disease (ADPKD) Yoshihisa Yamada¹, Hiroyuki Fujiki¹, Hiroshi Mizuguchi¹, Yukinobu Takeshita¹, Katsuji Hattori¹, Koji Ohmoto², Miki Aihara³, Keisuke Nagano⁴, Yoshitaka Yamamura⁵ ¹Dept. of Renal and Cardiovascular Research, Otsuka Pharmaceutical Co., Ltd., ²Dept. of Medical Innovation, Otsuka Pharmaceutical Co., Ltd., ³Medical Affairs, Otsuka Pharmaceutical Co., Ltd., ⁴Scientific Partnering, Otsuka Pharmaceutical Co., Ltd., ⁵Pharmaceutical Division, Otsuka Pharmaceutical Co., Ltd.

YIA

Depression, Anxiety (1)

1-Y-F1-115:3015:42 Chronic social defeat stress induces depression-like behavior through the decrease of GLT-1 ubiquitination in the mouse prefrontal cortex. Aika Kosuge¹, Kazuo Kunisawa¹, Tsubasa Iida¹, Bolati Wulaer^2,3, Willy Jaya Suento^3,4, Yasuko Yamamoto³, Kuniaki Saito^2,3,5, Akihiro Mouri^1,5, Toshitaka Nabeshima^2,5 ¹Dept. Regulatory Sci., Grad. Sch. Health Sci., Fujita Health Univ., ²Adv. Diagnostic. Syst. Res. Lab., Grad. Sch. Health Sci., Fujita Health Univ., ³Dept. Disease Control & Prevention., Grad. Sch. Health Sci., Fujita Health Univ., ⁴Dept. Psychiatry., Fac. Med., Hasanuddin Univ., ⁵NPO. J-DO.

1-Y-F1-215:4215:54 Induction of resilience for social stress mediating increased BDNF in the striatum by Shati/Nat8l Hajime Miyanishi¹, Shin-ichi Muramatsu^2,3, Atsumi Nitta¹ ¹Dept of Pharm Therap and Neuropharmcol, Fact of Pharmaceut Sci, Grad Univ of Med and Pharm Sci, Univ of Toyama, ²Div of Neuro Gene Therap, Open Innov Ctr, Univ of Jichi Med, ³Ctr for Gene & Cell Therap, Ins of Med Sci, Univ of Tokyo

1-Y-F1-315:5416:06 Subtype-specific dynamics and roles for chronic stress-induced mobilization of leukocytes Ishikawa Yuka^1,2, Shiho Kitaoka¹, Taro Kato², Tomoyuki Furuyashiki¹ ¹Div. of Pharmacol., Grad. Sch. of Med., Kobe Univ., ²Pharmacol. Res. Unit, Sumitomo Dainippon Pharma Co., Ltd.

1-Y-F1-416:0616:18 Kamikihito enhances cognition and improves anhedonia-like traits in aged C57BL/6J mice Hiroaki Oizumi, Shinji Miyazaki, Yuji Omiya, Yoshiki Ikeda Tsumura Kampo Research Laboratories, Tsumura & Co.

YIA

Learning, Memory, Cognition (2), Psychiatry, Behavior (1)

1-Y-F2-116:3016:42 Selective δ-opioid receptor agonist, KNT-127, facilitates extinction learning of contextual fear via fear circuitry in mice. Ayako Kawaminami¹, Daisuke Yamada¹, Shoko Yanagisawa¹, Motoki Shirakata¹, Keita Iio², Hiroshi Nagase², Akiyoshi Saitoh¹ ¹Lab Pharmacol, Fac Pharm Sci, Tokyo Univ of Science, ²IIIS, Univ of Tsukuba

1-Y-F2-216:4216:54 Reactivation of hippocampal place cells in reward and sleep Saichiro Yagi¹, Yuji Ikegaya^1,2,3, Takuya Sasaki^1,4 ¹Lab. Chem. Pharmacol., Grad. Sch. Pharmaceut. Sci., Univ. Tokyo, ²Institute for AI and Beyond, The University of Tokyo, ³Center for Information and Neural Networks, National Institute of Information and Communications Technology, ⁴Precursory Research for Embryonic Science and Technology

1-Y-F2-316:5417:06 NOX1/NADPH oxidase regulates compulsive-like repetitive behaviors through promoting D₂ receptor-mediated synaptic facilitation in the striatum Nozomi Asaoka¹, Masakazu Ibi¹, Shuji Kaneko², Chihiro Yabe¹ ¹Dept. Pharmacol., Grad. Sch. Med., Kyoto Pref. Univ. Med., ²Dept. Mol. Pharm., Grad. Sch. Pharm. Sci., Kyoto Univ.

1-Y-F2-417:0617:18 High salt intake induces hypertension and abnormal behaviors with peripheral inflammatory response Hisayoshi Kubota¹, Akihiro Mouri^1,6, Kazuo Kunisawa¹, Masaya Hasegawa¹, Hitomi Kurahashi¹, Yasuko Yamamoto², Hiroyuki Tezuka³, Masanori Kugita⁴, Shizuko Nagao⁴, Kuniaki Saito^2,5,6, Toshitaka Nabeshima^5,6 ¹Dept. Regulatory Sci., Grad. Sch. Health Sci., Fujita Health Univ., ²Dept. Disease Control & Prevention., Grad. Sch. Health Sci., Fujita Health Univ., ³Res. Promotion & Support Headquarters., Fujita Health Univ., ⁴Educ & Res. Ctr. Anim. Models. Hum. Diseases., Fujita Health Univ., ⁵Adv. Diagnostic. Syst. Res. Lab., Grad. Sch. Health Sci., Fujita Health Univ., ⁶NPO. J-DO

YIA

Psychiatry, Behavior (2)

1-Y-F3-117:3017:42 Involvement of amygdalar NPY and glutamatergic functions in impaired social behavior in diabetic mice Naomi Yonemochi¹, Daiki Ueda¹, Tomohiro Kamata¹, Junzo Kamei², Hiroko Ikeda¹ ¹Dept. Pathophysiol. Ther., Hoshi Univ. Sch. Pharm. Pharmaceut. Sci., ²Dept. Biomol. Pharmacol., Hoshi Univ. Sch. Pharm. Pharmaceut. Sci.

1-Y-F3-217:4217:54 NOX1/NADPH oxidase affects the development of autism-like behaviors in a maternal immune activation model Xueqing Zhang, Masakazu Ibi, Chihiro Yabe-Nishimura Dept. Pharmacol. Kyoto Prefectural University of Medicine

1-Y-F3-317:5418:06 Childcare behavior study using computer vision and deep learning analysis Sajjaviriya Chortip, Morio Azuma, Hiroyoshi Tsuchiya, Taka-aki Koshimizu Div. Mol. Pharmacol., Jichi Med. Univ.

1-Y-F3-418:0618:18 Effects of a Rho-kinase inhibitor, fasudil on schizophrenia-like behavior and neurotransmitter release in MK-801-treated mice Rinako Tanaka¹, Masahito Sawahata¹, Saeko Takase¹, Yue Liu¹, Kazuhiro Hada¹, Hiroyuki Mizoguchi¹, Taku Nagai¹, Toshitaka Nabeshima², Norio Ozaki³, Kiyofumi Yamada¹ ¹Dept. Neuropsychopharmacol. Hosp. Pharm., Nagoya Univ. Grad. Sch. Med., Nagoya, Japan, ²Adv. Diag. Sys. Res. Lab., Grad. Sch. Health Sci., Fujita Health Univ., Toyoake, Japan, ³Dept. Psychiatry, Nagoya Univ. Grad. Sch. Med., Nagoya, Japan