program｜The 94th Annual Meeting of the Japanese Pharmacological Society

Symposium4

Cutting edge of respiratory research: COVID-19, pulmonary hypertension, and molecular mechanisms

1-S04-19:0010:30 Diversity of roles of nitric oxide synthases in the pathogenesis of lung diseases Masato Tsutsui¹, Kaori Kato², Takaaki Ogoshi², Shingo Noguchi², Kazuhiro Yatera² ¹Dept. Pharmacol, Ryukyu Univ. Grad. Sch. Med., ²Dept. Respir. Med., Sch. Med., Univ. Occup. Environ. Health

1-S04-29:0010:30 Importance of NO-cGMP-PKG Axis in Pulmonary Arterial Hypertension Hiroshi Watanabe Hamamatsu University School of Medicine

1-S04-39:0010:30 Treatment of COVID-19 Kazuhiro Yatera Dept. Respiratory Med., Univ. Occupational & Environmental Health

1-S04-49:0010:30 Molecules involved in high vascular permeability lung edema associated acute lung injury Yuichi Hattori¹, Kohshi Hattori² ¹Health Sciences University of Hokkaido, ²The University of Tokyo Hospital

Joint Symposium

The emerging view of exposome study with pharmacological/toxicological approaches

1-S10-110:3012:00 A modeling of environmental electrophile exposome Yoshito Kumagai Environmental Biology Section, Faculty of Medicine, University of Tsukuba

1-S10-210:3012:00 Natural antibodies as a safeguard against exposome Koji Uchida The University of Tokyo

1-S10-310:3012:00 Regulation of pattern recognition receptors and environmental stress responses by reactive sulfur species Tomohiro Sawa Dept. Microbiol., Grad. Sch. Med. Sci., Kumamoto Univ.

1-S10-410:3012:00 From lysine acyl modifications to lysine adduct exposome Akihiro Ito Tokyo Univ. Pharm. Life Sci.

YIA

Kidney, Urination (1)

1-Y-E1-115:3015:42 Applicability of “NORD-1,” a light-reactive NO releaser, to the lower urinary tract dysfunction Kotomi Maeda¹, Yuji Hotta¹, Naoya Ieda², Tomoya Kataoka³, Hidehiko Nakagawa², Kazunori Kimura^1,3 ¹Dept. Hospital Pharm., Grad. Sch. Pharm. Sci., Nagoya City Univ., ²Dept. Organic & Medicinal Chem., Grad. Sch. Pharm. Sci., Nagoya City Univ., ³Dept. Clinical Pharm., Grad. Sch. Med. Sci., Nagoya City Univ.

1-Y-E1-215:4215:54 High salt diet enhanced cholinergic components-induced contractile responses of detrusor muscle in Dahl salt-sensitive rats Ryoya Kawata¹, Yuji Hotta¹, Kotomi Maeda¹, Tomoya Kataoka², Kazunori Kimura^1,2 ¹Dept. Hospital Pharm., Grad. Sch. Pharm. Sci., Nagoya City Univ., ²Dept. Clinical Pharm., Grad. Sch. Med. Sci., Nagoya City Univ.

1-Y-E1-315:5416:06 Generation of novel hypertension-diabetic nephropathy mice model and ameliorative effect of PDE 4 and 5 inhibitors. Yasunori Nio Takeda Pharmaceutical Company

1-Y-E1-416:0616:18 Acute kidney injury-induced ZBTB38 contributes to tubular cell loss. Takeo Harada¹, Masanori Obana¹, Yosiaki Miyake¹, Ayaha Yamamoto¹, Hiroyasu Kamuro¹, Syota Tanaka¹, Makiko Maeda^1,2, Yasushi Fujio^1,2 ¹Laboratory of Clinical Science and Biomedicine, Grad. Sch. Pharm., Osaka Univ., ²Laboratory of Clinical Pharmacology and Therapeutics, Grad. Sch. Pharm., Osaka Univ.

YIA

Receptor, Channel, Transporter (1), Drug treatment (1)

1-Y-E2-116:3016:42 Effects of various 5-HT₃receptor antagonists on cisplatin-induced acute kidney injury Masaya Kanda¹, Mitsuhiro Goda³, Toshihiko Yoshioka^1,2, Ami Yoshida¹, Takahiro Nimura¹, Yoshito Zamami^1,2, Yuki Ishizawa⁴, Kenta Yagi³, Hirohumi Hamano², Naoto Okada², Keisuke Ishizawa^1,2 ¹Dept. Clin. Pharmacol. Ther., Grad. Sch. Biomed. Sci., Tokushima Univ.,, ²Dept. Pharm., Tokushima Univ. Hosp.,, ³Clin. Res. Ctr. Dev. Ther., Tokushima Univ. Hosp.,, ⁴AWA Support Ctr, Tokushima Univ.,

1-Y-E2-216:4216:54 A drug repositioning approach against cisplatin-induced nephrotoxicity. Eri Wakai, Yuya Suzumura, Yuhei Nisimura Department of Integrative Pharmacology, Mie University Graduate School of Medicine

1-Y-E2-316:5417:06 Vitamin E induces palmitoylation of 67kDa laminin receptor by direct binding . Seika Okamoto¹, Daiki Hayashi^1,2, Naoko Adachi³, Mouchlis Varnavas², Shuji Ueda¹, Minoru Yamanoue¹, Dennis Edward², Toshiki Ito³, Naoaki Saito³, Yasuhito Shirai¹ ¹Dept. of Appl. Chem.in Biosci.,Kobe Univ., ²Dept. of Chem.,UCSD, ³Biosignal Res. Ctr.,Kobe Univ.

1-Y-E2-417:0617:18 HMG-CoA reductase inhibitor ameliorate oxaliplatin-induced peripheral neuropathy via GST in peripheral neuron Fuka Aizawa¹, Yoshito Zamami^1,2, Takahiro Niimura², Takehiro Kawashiri³, Mitsuhiro Goda⁴, Kenta Yagi⁴, Yuki Izawa-Ishizawa⁵, Keisuke Ishizawa^1,2 ¹Department of Pharmacy, Tokushima University Hospital, ²Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, ³Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University, ⁴Clinical Research Center for Developmental Therapeutics, Tokushima University Hospital, ⁵AWA Support Center, Tokushima University

YIA

Cancer, Chemotherapy, Antibody Therapy (1), Drug treatment (2)

1-Y-E3-117:3017:42 Therapeutic potency and mechanisms of polyI:C in triple negative breast cancer Tamura Yusuke, Masato Morikawa, Ryo Tanabe, Daizo Koinuma, Kohei Miyazono Dept. Mol. Path., Grad. Sch. Med., Univ. Tokyo

1-Y-E3-217:4217:54 Biological significance of CYLD downregulation in Triple negative breast cancer. Kuwano Akari¹, Chika Hirai¹, Naoki Suenaga¹, Ayumi Kanemaru¹, Hitomi Arakaki¹, Mitsuhiro Hayashi², Chika Saigou^1,3, Hideyuki Saitou^1,3, Hirofumi Jono^1,3 ¹Dept. Clinical Pharmaceutical Sciences, Kumamoto Univ. Grad. Sch. Pharm., ²Dept. Breast and Endocrine Surgery, Kumamoto Univ. Grad. Sch. Med., ³Dept. Pharm. Kumamoto Univ.

1-Y-E3-317:5418:06 Development of a novel epitope mapping method (REMAP) using RIEDL tag system Asano Teizo, Mika Kaneko, Yukinari Kato Dept. Antibody Drug Development, Tohoku University Grad. Sch. of Med.

1-Y-E3-418:0618:18 Construction of biologically-interpretable chemical–disease association focused on transcription factors organizing chemically-perturbed genes Zou Zhaonan¹, Michio Iwata², Yoshihiro Yamanishi², Shinya Oki¹ ¹Dept Drug Discov Med, Grad Sch Med, Kyoto Univ, ²Dept Biosci Bioinform, Fac Comp Sci Syst Eng, Kyushu Inst Tech