program｜The 94th Annual Meeting of the Japanese Pharmacological Society

Symposium1

Aiming for prevention and treatment of aggravation of emerging virus infections ~Thinking from COVID-19 countermeasures~

1-S01-19:0010:30 Drug Screening for COVID-19 using Supercomputer “Fugaku” Yasushi Okuno Dept. of Biomed. Data Intelligence, Grad.Sch. of Med., Kyoto Univ.

1-S01-29:0010:30 Construction of the multi-layer omics data generation / analysis platform that contributes to the precision medicine of COVID-19 Yumiko Imai National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN)

1-S01-39:0010:30 Eco-pharma research aimed at developing COVID-19 therapeutic agent Kato Yuri¹, Motohiro Nishida^1,2 ¹Dept. Physiol., Grad. Sch. Pharm. Sci., Kyushu Univ., ²Div. Cardio., NIPS

1-S01-49:0010:30 Efficacy and safety of anti-COVID-19 drug candidates Yasunari Kanda¹, Hiroshi Asakura² ¹Div Pharmacol, NIHS, ²Div Biomed Food Res, NIHS

Company-Organized Symposium

New Effort to New Drug Approval to Treat COVID-19; Drug Repositioning Approach

1-S07-110:3012:00 COVID-19 Drug Candidate Pipeline, An Overview Hiroyuki Sugiyama Taisho Pharmaceut. Discovery Lab. Pharmacol. 2

1-S07-210:3012:00 Remdesivir for COVID-19 Yasuhisa Fujita Medical Affairs, Gilead Sciences K.K.

1-S07-310:3012:00 Contribution to Development of Remedies for COVID-19: Focusing on Eritoran Kappei Tsukahara Eisai Co., Ltd.

1-S07-410:3012:00 Drug repositioning to combat COVID-19 using artificial intelligence system Norihisa Shindo, Hiroyoshi Toyoshiba FRONTEO, Inc

Oral Sessions

Immunity, Inflammation, Allergy (1) , Itch

1-O-B1-115:3015:42 Possible Involvement of PACAP-PAC1 Receptor Signaling System to Itch Sensation in Mice. Ichiro Takasaki¹, Sho Kato¹, Ryuta Ikeda¹, Mayuko Murata¹, Hiroki Saito², Yuki Kambe², Hiroaki Gouda³, Takuya Okada⁴, Naoki Toyooka⁴, Atsuro Miyata², Takashi Kurihara² ¹Dept. Pharmacol., Grad. Sch. Sci. Eng., Univ. Toyama, ²Dept. Pharmacol., Grad. Sch. Med. Dent., Kagoshima Univ., ³Dept. Analytical and Physical Chem., Sch. Pharmacy., Showa Univ., ⁴Dept. Bio-func. Mol. Eng., Grad. Sch. Sci. Eng., Univ. Toyama

1-O-B1-215:4215:54 Role of MrgprA3-expressing primary sensory neurons in itch responses in atopic dermatitis model mice Masanori Fujii, Kyoko Fujii, Ryosuke Miyagawa, Satoshi Tanaka Dept. Pharmacol., Kyoto Pharm. Univ.

1-O-B1-315:5416:06 Involvement in serotonin receptor subtypes on spontaneous itch-related behavior in mice with atopy-like dermatitis Tsugunobu Andoh^1,2, Takeshi Osaki², Daisuke Uta², Yasushi Kuraishi³, Toshiaki Kume² ¹Dept. Pharmacol. Pathophysiol., College Pharm., Kinjo Gakuin Univ., ²Dept. Applied Pharmacol., Sch. Med. Pharm. Sci., Univ. Toyama, ³Wakayama Med. Univ.

1-O-B1-416:0616:18 Evaluation of the anti-inflammatory and anti-pruritic responses of fish oil in a mouse model of dermatitis Fukuyama Tomoki¹, Chiharu Hayakawa¹, Masaharu Kiyosue² ¹Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Azabu University, ²Oriental Yeast Co., Ltd.

Oral Sessions

Pain, Sensory Neuron (1)

1-O-B2-116:3016:42 Histamine activation of periaqueductal grey matter and somatosensory cortex exerts an antinociceptive effect in mechanical allodynia. Mei Yu¹, Takeo Yoshikawa¹, Fumito Naganuma², Kazuhiko Yanai¹ ¹Dept Pharmacol. Sch Med. Tohoku Univ., ²Div Pharmacol. Fac Med. Tohoku Med and Pharmaceut Univ.

1-O-B2-216:4216:54 A thrombin inhibitor aggravates HMGB1-dependent colonic and bladder pain: Role of the thrombomodulin/thrombin system in visceral pain modulation Ayumu Yamagata¹, Kazuki Matsui¹, Maho Tsubota¹, Masahiro Nishibori², Atsufumi Kawabata¹ ¹Lab. Pharmacol. Pathophysiol., Fac. Pharm., Kindai Univ., ²Dept. Pharmacol., Okayama Univ. Grad. Sch. Med.

1-O-B2-316:5417:06 Exacerbation of paclitaxel-induced peripheral neuropathy and HMGB1-induced allodynia in ovariectomized mice Ayano Kanto¹, Shiori Hiramoto¹, Maho Tsubota¹, Hiroaki Matsunaga¹, Tomoyoshi Miyamoto^1,2, Yuichi Koizumi², Masahiro Nishibori³, Atsufumi Kawabata¹ ¹Lab. Pharmacol. Pathophysiol., Fac. Pharm., Kindai Univ., ²Dept. Pharm., Seichokai Fuchu Hospital, ³Dept. Pharmacol., Okayama Univ. Grad. Sch. Med.

1-O-B2-417:0617:18 Sex-dependent suppressive effects of PLX3397, a microglial inhibitor, on nerve injury-induced neuropathic pain in mice Norikazu Kiguchi¹, Kentaro Suzuki² ¹Dept. Pharmacol., Sch. Med., Wakayama Med. Univ., ²Dept. Development. Genet., Inst. Adv. Med., Wakayama Med. Univ.

Oral Sessions

Glia Cell (1)

1-O-B3-117:3017:42 Sex-dependent pain-regulatory effects of spinal microglia using Gi / Gq DREADD systems in mice Fumihiro Saika, Norikazu Kiguchi, Shinsuke Matsuzaki, Tomoe Nishitani-Nakamura Dept. Pharmacol. Wakayama Med Univ.

1-O-B3-217:4217:54 Astrocytic histamine N-methyltransferase controls locomotor activity and vigilance state Rina Otsuka¹, Fumito Naganuma², Yuki Sato¹, Yuna Takahashi¹, Kazuhiko Yanai¹, Takeo Yoshikawa¹ ¹Dept. Pharmacol., Grad. Sch. Med., Tohoku Univ., ²Div. Pharmacol., Fac. Med., Tohoku Med. Pharmaceut. Univ.

1-O-B3-317:5418:06 Astrocytic mGluR5 controls microglial phagocytosis in the critical period, which fates a lifelong cortical circuits Yosuke Danjo¹, Youichi Shinozaki^1,2, Parajuli Bijay^1,2, Ken-Ichi Dewa³, Yuto Kubota¹, Takahiro Segawa⁴, Eiji Shigetomi^1,2, Koizumi Schuichi^1,2 ¹Dept Neuropharmacol, Interdiscip Grad Sch Med, Univ Yamanashi,, ²Yamanashi Interdiscipinary Brain-Immune Research Center,, ³Dept Biochem and Cell Biol, Natl Inst Neurosci, NCNP,, ⁴Cent Life Sci Res., Univ. Yamanashi,

1-O-B3-418:0618:18 Positive effect of microglia repopulation on the Alexander disease pathology, the primary astrocyte disease Kenji Kobayashi¹, Eiji Shigetomi¹, Bijay Parajuli¹, Yuto Kubota¹, Kozo Saito¹, Kenji Tanaka², Kazuhiro Ikenaka³, Schuichi Koizumi¹ ¹Dept Neuropharmacol, Interdiscipl Grad Sch Med, Univ Yamanashi, ²Dept Neuropsych, Keio Univ Sch Med., ³Div Neurobiol and Bioinfo, NIPS

1-O-B3-518:1818:30 Implication of glutamine-glutamate metabolic change in astrocyte via cGAMP transmitted by metastatic cancer cells Hiromi Sato¹, Toya Okawa¹, Kurumi Hara¹, Kyoko Goto¹, Moe Kikuchi¹, Hiroki Tanaka², Daiki Shirane², Takuma Yamakawa², Hidetaka Akita², Hiroto Hatakeyama¹, Akihiro Hisaka¹ ¹Clinical Pharmacology & Pharmacometrics, Grad. Sch. Pharmaceut. Sci., Chiba Univ., ²Design and Drug Disposition, Grad. Sch. Pharmaceut. Sci., Chiba Univ.