program｜The 94th Annual Meeting of the Japanese Pharmacological Society

JPS Symposium

JPS symposium: A memorial symposium for Prof Burnstock -Pharmacology of purinergic signaling, past and future-

1-S03-19:0010:30 Overview for the study of P2 Receptors: From P2 Receptor History to Neuropathic Pain Studies Kazuhide Inoue The Institute for Advanced Study of Kyushu University

1-S03-29:0010:30 Adenosine A2A Receptor Antagonists for Parkinson’s Disease Treatment: 18 Years Adventure Jiang-Fan Chen^1,2 ¹Wenzhou Medical Univ, China, ²Boston Univ Sch Med, USA

1-S03-39:0010:30 Purine signaling complex - the birth and development of the concept Fusao Kato Dept Neurosci, Jikei Univ Sch Med

1-S03-49:0010:30 Dysfucntion of glial purinergic signals and depression Schuichi Koizumi¹ ¹Dept Neuropharmacol, Grad Sch Med, Univ Yamanashi, ²YiBIC

Symposium11

Cutting edge research on neurologic and psychiatric diseases focusing on targeted neurons and glial cells by applying a cell subtype-specific differentiation technique

1-S09-110:3012:00 Robust Platform of Neuronal Subtype-specific Differentiation Using Transcription Factors for in vitro Screening Applications Mitsuru Ishikawa, Hideyuki Okano Dept. Physiol. Keio Univ. Sch. Med.

1-S09-210:3012:00 Abnormalities of microglial differentiation in neuropsychiatric disorders: translational research using human blood-derived iMG cells Takahiro A. Kato Dept. Neuropsychiatry, Grad. Sch. Med. Sci. Kyushu Univ.

1-S09-310:3012:00 Modeling of psychiatric and neurodevelopmental disorders using iPSC technology Takanobu Nakazawa Dept Biosci, Tokyo Univ of Agr

1-S09-410:3012:00 Elucidation of the mechanisms of intractable neurologic diseases by applying techniques for the differentiation of iPS cells and reverse translational neuroscience research Naoko Kuzumaki¹, Yukari Suda^1,2, Takahiro Kato³, Hideyuki Okano⁴, Minoru Narita^1,2 ¹Dept. Pharmacol., Hoshi Univ., Tokyo, Japan, ²Div. Pathophysiol., Natl. Cancer Ctr. Res. Inst. Tokyo, Japan, ³Dept. Neuropsychiatry, Grad. Sch. Med. Sci., Kyushu Univ., Fukuoka, Japan, ⁴Dept. Physiol., Keio Univ. Sch. Med. Tokyo, Japan

Oral Sessions

Heart function, Heart failure (1)

1-O-D1-115:3015:42 Activation of YAP is essential for the myocardial recovery from myocarditis Shoki Fukuyama¹, Yusuke Kametani¹, Yuriko Wada¹, Shota Suzuki¹, Ayaka Umeda¹, Makiko Maeda², Shota Tanaka¹, Masanori Obana¹, Yasushi Fujio¹ ¹Laboratory of Clinical Science and Biomedicine., Grad. Sch. Pharm., Osaka Univ., ²Laboratory of Clinical Pharmacology and Therapeutics., Grad. Sch. Pharm., Osaka Univ.

1-O-D1-215:4215:54 Cardioprotective roles of novel cell death inhibitor, defender against cell death 1 (Dad1) Shota Mori¹, Shota Tanaka¹, Makiko Maeda², Masanori Obana¹, Yasushi Fujio^1,2 ¹Laboratory of Clinical Science and Biomedicine, Grad. Sch. Pharm., Osaka Univ., ²Laboratory of Clinical Pharmacology and Therapeutics, Grad. Sch. Pharm., Osaka Univ.

1-O-D1-315:5416:06 Regulation of fibrosis inhibitory factors by NOX1/NADPH oxidase in H9c2 cardiomyocytes Kazumi Iwata, Chihiro Yabe-Nishimura Dept. Pharmacol., Kyoto Pref. Univ. Med.

1-O-D1-416:0616:18 2,5-Dimethylcelecoxib attenuates cardiac remodeling after cryoinjury-induced myocardial infarction by suppressing the fibroblast-myofibroblast transformation Ikushima Eigo¹, Shin Ishikane¹, Takehiro Kishigami¹, Hiroaki Matsunaga¹, Tomohiro Takiguchi², Yumiko Toyohira¹, Fumi Takahashi-Yanaga¹ ¹Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan., ²Department of Clinical Pharmacology, Graduate School of Medical Sciences, Kyushu University

Oral Sessions

Heart function, Heart failure (2)

1-O-D2-116:3016:42 Molecular mechanisms of Doxorubicin-induced cardiomyopathy, involvement in the impairment of mitophagy Takeya Sato¹, Mikio Muraoka¹, Noriko Toda^1,2, Guanjie Li¹, Masanori Yamauchi², Masaki Saito¹, Teruyuki Yanagisawa¹ ¹Dept. Mol. Pharm. Tohoku Univ. Grad.Sch. Med., ²Dept. Anesthesiol. Perioperat. Med. Tohoku Univ. Grad.Sch. Med

1-O-D2-216:4216:54 Induction of Autophagy Attenuates Imatinib-induced Cardiotoxicity Miyuki Kobara, Hiroe Toba, Tetsuo Nakata Department of Clinical Pharmacology, Kyoto Pharmaceutical University

1-O-D2-316:5417:06 Oncocardiology of Anticancer Molecular Target Drugs Kayoko Yamada^1,2, Kyoko Yamamoto^1,2, Yuka Mizutani^1,2, Noriko Ichino^1,2, Aoi Mori^1,2, Yukiko Kato^1,2, Yasuhito Shimada³, Yuhei Nishimura³, Toshio Tanaka^1,2 ¹Department of Systems Pharmacology Mie University Graduate School of Medicine, ²Mie University Medical Zebrafish Research Center, ³Department of Integrative Pharmacology Mie University Graduate School of Medicine

1-O-D2-417:0617:18 Cancer cachexia-induced myocardial impairment could be improved by voluntary wheel running Miki Nonaka¹, Susumu Ueno², Ryo Kakigi³, Nagomi Kurebayashi⁴, Takashi Murayama⁴, Kanako Miyano⁵, Kiyoshi Terawaki⁶, Takashi Sakurai⁴, Yasuhito Uezono¹ ¹Dept. Pain Control Res., Jikei Univ. Sch. Med., ²Dept. Occup. Toxicol., Inst. Ind. Ecol. Sci., Univ. Occup. Environ. Hlth., ³Fac. Management & Information Sci, Josai International University, ⁴Dept. Pharmacol., Juntendo Univ. Sch. Med., ⁵Div. Pathophysiol., Natl. Cancer Ctr. Res. Inst., ⁶Tsumura Res. Labo., Tsumura & Co.

Oral Sessions

Arrhythmia, Channel

1-O-D3-117:3017:42 Effects of RyR2 specific inhibitors on arrhythmia in CPVT model mice Nagomi Kurebayashi¹, Takashi Murayama¹, Koichiro Ishii¹, Masato Konishi¹, Masami Sugihara², Shuichi Mori³, Hiroto Iinuma³, Mari Ishigami-Yuasa³, Nobuyuki Murakoshi⁴, Hiroyuki Kagechika³, Takashi Sakurai¹ ¹Dept Cell Mol Pharmacol, Juntendo Univ Grad Sch Med, ²Dept Clin Lab Med, Juntendo Univ Gad Sch Med, ³IBB, Tokyo Med Dent Univ, ⁴Dept Cardiol, Fac Med, Univ Tsukuba

1-O-D3-217:4217:54 Cardiac safety pharmacological characteristics of class Id antiarrhythmic drug ranolazine in the halothane-anesthetized dog Yoshio Nunoi^1,2, Ryuichi Kambayashi¹, Ai Goto¹, Yoshiki Hirokawa¹, Hiroko Izumi-Nakaseko¹, Mihoko Hagiwara-Nagasawa¹, Yoshinori Takei³, Akio Matsumoto⁴, Shinichi Kawai⁵, Yoshinori Watanabe², Atsushi Sugiyama^1,3,4,5 ¹Dept. Pharmacol., Faculty Med., Toho Univ., ²Div. Cardiovasc. Surg., Dept. Surg., Faculty Med, Toho Univ., ³Dept. Translational Research & Cellular Therapeutics, Faculty Med., Toho Univ., ⁴Dept. Aging Pharmacol., Faculty Med., Toho Univ., ⁵Dept. Inflammation & Pain Control Research, Faculty Med., Toho Univ.

1-O-D3-317:5418:06 Analysis of onset mechanisms on clinically reported, lamotrigine-induced cardiovascular adverse events as a reverse translational research using the halothane-anesthetized dogs Ai Goto¹, Yoshiki Hirokawa¹, Yoshio Nunoi², Ryuichi Kambayashi², Hiroko Izumi-Nakaseko^1,2, Mihoko Hagiwara-Nagasawa², Akio Matsumoto³, Yoshinori Takei⁴, Shinichi Kawai⁵, Atsushi Sugiyama^1,2,3,4,5 ¹Dept. Pharmacol., Grad. Sch. Med., Toho Univ., ²Dept. Pharmacol., Faculty. Med., Toho Univ., ³Dept. Aging Pharmacol., Faculty. Med., Toho Univ., ⁴Dept. Translational Research & Cellular Therapeutics., Faculty. Med., Toho Univ., ⁵Dept. Inflammation & Pain Control Research, Faculty. Med., Toho Univ.

1-O-D3-418:0618:18 Electropharmacological effects of licorice decoction on the heart: integral assessment using in vitro and in vivo models Hiroko Izumi-Nakaseko¹, Koki Chiba², Ai Goto¹, Ryuichi Kambayashi¹, Yoshio Nunoi¹, Mihoko Hagiwara-Nagasawa¹, Akio Matsumoto³, Yoshinori Takei⁴, Shinichi Kawai⁵, Atsushi Sugiyama^1,3,4,5 ¹Dept. Pharmacol., Faculty. Med., Toho Univ., ²Dept. Trad. Med., Faculty Med., Toho Univ., ³Dept. Translational Research & Cellular Therapeutics, Faculty Med., Toho Univ., ⁴Dept. Aging Pharmacol., Faculty Med., Toho Univ., ⁵Dept. Inflammation & Pain Control Research, Faculty Med., Toho Univ.

1-O-D3-518:1818:30 Nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity. Mikiko Ohno¹, Hiroshi Matsuura², Takeru Makiyama³, Yasuhiko Koujitani³, Kiyoto Nishi³, Hirotaka Iwasaki¹, Shintaro Matsuda³, Takeshi Kimura³, Eiichiro Nishi¹ ¹Dept. Pharm. Shiga Univ. Med. Sci., ²Dept. Phisio. Shiga Univ. Med. Sci., ³Dept. Cardiovasc. Med, Grad. Sch. Med., Kyoto Univ.

March 8 (Mon) Room D