program｜The 94th Annual Meeting of the Japanese Pharmacological Society

Young Scientists Symposium

Central mechanisms of stress-related diseases approaching from stress responses

1-S02-19:0010:30 Proposal of a novel mechanism of depression caused by chronic stress: Disruption of energy metabolism in the brain Yuki Kambe, Takashi Kurihara, Atsuro Miyata Dept. Pharmacol., Grad. Sch. Med. Dent. Sci., Kagoshima Univ.

1-S02-29:0010:30 The regulation of synaptic transmission through intracellular acetylcholine receptor: possible interaction with stress Takayoshi Masuoka¹, Junsuke Uwada², Takaharu Ishibashi¹, Ikunobu Muramatsu¹ ¹Dept. Pharmacol., Kanazawa Med. Univ., Sch. Med., 1-1 Daigaku, Uchinada, Ishikawa, 920-0293, Japan, ²Div. Cell. Signal Transduct., Dept. Biochem., Asahikawa Med. Univ., Sch. Med., Asahikawa, Hokkaido, 078-8510, Japan

1-S02-39:0010:30 Role of alpha-adrenoceptor subtypes in the regulation of ovarian hormone secretion and stress Fusako Kagitani^1,2, Sae Uchida² ¹Univ. Human Arts Sci., ²Dept. Auton. Neurosci., Tokyo Metropol. Inst. Gerontol.

1-S02-49:0010:30 Roles of brain 2-arachidonoylglycerol in regulation of the sympatho-adrenomedullary outflow Takahiro Shimizu, Shogo Shimizu, Youichirou Higashi, Motoaki Saito Dept. of Pharmacol., Kochi Med. Sch., Kochi Univ.

Symposium8

Hierarchical understanding of stress-induced brain pathology

1-S08-110:3012:00 Subcellular mechanisms of social stress Hirotaka Nagai, Tomoyuki Furuyashiki Div Pharmacol Kobe Univ Grad Sch Med

1-S08-210:3012:00 Whole-brain mapping of activated neurons and circuits in brains after exposure to acute stressors Misaki Niu¹, Atsushi Kasai¹, Kaoru Seiriki^1,2, Hitoshi Hashimoto^1,3,4,5,6 ¹Lab. Mol. Neuropharmacol., Grad. Sch. Pharmaceut. Sci., Osaka Univ., ²Inst. Transdiscip. Grad. Degree Prog., Grad. Sch. Pharmaceut. Sci., Osaka Univ., ³Unit. Grad. Sch. Child Dev., Osaka Univ., ⁴Inst. Datability Sci., Osaka Univ., ⁵Open Tarnsdiscip. Res. Initi., Osaka Univ., ⁶Dep. Mol Pharmaceut. Sci., Grad. Sch. Med., Osaka Univ.

1-S08-310:3012:00 Memory consolidation as a mechanism to amplify stress-induced responses Takuya Sasaki Lab. Chem. Pharmacol., Grad. Sch. Pharm., Tokyo Univ.

1-S08-410:3012:00 Epigenetic mechanisms of stress resilience and susceptibility and its implications for drug development Shusaku Uchida Kyoto Univ, MIC

Oral Sessions

Cerebral Circulation, Metabolism, Ischemia (1)

1-O-C1-115:3015:42 Establishment of meteoropathy model mice Yuki Kurauchi^1,2, Risako Tanaka², Sumika Ryu², Makito Haruta³, Kiyotaka Sasagawa³, Takahiro Seki^1,2, Jun Ohta³, Hiroshi Katsuki^1,2 ¹Dept Chemico-Pharmcol Sci, Grad Sch Pharm Sci, Kumamoto Univ, ²Dept Chemico-Pharmacol Sci, Sch Pharm, Kumamoto Univ, ³Division of Materials Science, Graduate School of Science and Technology, Nara Institute of Science and Technology

1-O-C1-215:4215:54 Protective effects of protein SUMOylation on BBB permeability in therapeutic hypothermia for ischemic brain injury Tanaka Yuta, Mayuko Monden, Masatomo Watanabe, Yutaka Tamura Dept. Pharmacol., Fac. Pharm. & Pharmaceut. Sci., Fukuyama Univ.

1-O-C1-315:5416:06 Roles of DNA methylation in neuronal cell death after ischemic injury Mayumi Asada¹, Hideki Hayashi¹, Kenjiro Murakami¹, Kento Kikuiri¹, Ryotaro Kaneko¹, Bo Yuan², Norio Takagi¹ ¹Dept. Appl. Biochem., Sch. Pharm., Tokyo Univ. Pharm. and Life Sci., ²Lab. Pharmacol., Fac. Pharm. and Pharmaceut. Sci., Sch. Pharm., Josai Univ.

1-O-C1-416:0616:18 The efficacy and safety of a laser thrombolytic system in an animal thrombosis model Yuji Matsumoto¹, Daisuke Yamashita², Yoshiyuki Shimizu², Yohei Takata², Tsuyoshi Kosugi², Yoshinori Tamaoki², Hiroyuki Okada², Teiji Nakayama³, Kazuo Umemura¹ ¹Dep. Pharmacol., Hamamatsu Univ. Sch. Med., ²Hamamatsu Photonics K.K., ³Dep. Neurosurg., Hamamatsu Medical Center

Oral Sessions

Cerebral Circulation, Metabolism, Ischemia (2)

1-O-C2-116:3016:42 Prenatal hypoxic stress caused the decrease of astrocytes in the neurodevelopmental disorder-related region of rat brain Kentaro Tokudome¹, Masaaki Ueki^1,2, Takehiro Yamaguchi¹, Shinji Matsunaga¹, Shuhei Tomita¹ ¹Dept. Pharmacol., Grad. Sch. Med., Osaka City Univ., ²Dep. Anesthesiol., Nishiwaki Municipal Hospital

1-O-C2-216:4216:54 Effect of voluntary exercise after cerebral ischemia on functional recovery and the peri-infarct cortex Natsumi Yamaguchi¹, Kae Fukumoto¹, Toshinori Sawano¹, Jin Nakatani¹, Daijiro Yanagisawa², Ikuo Tooyama², Hidekazu Tanaka¹ ¹Lab. Pharmacol., Grad. Sch. Life Sci., Ritsumeikan Univ., ²Dept. Diag. and Therap. for Brain Dis., Mol. Neurosci. Res. Ctr., Shiga Univ. Med. Sci.

1-O-C2-316:5417:06 Function of novel Iba1-positive cells appearing in the ischemic core Toshinori Sawano¹, Natsumi Yamaguchi¹, Jin Nakatani¹, Shinobu Inagaki^2,3, Takayuki Nakagomi⁴, Tomohiro Matsuyama⁴, Hidekazu Tanaka¹ ¹Lab. Pharmacol., Grad. Sch. Life Sci., Ritsumeikan Univ., ²United Grad. Sch. Child Develop., Osaka Univ., ³Dept. PT., Yukioka Col. Health Sci., ⁴Lab. Neurogenesis and CNS Repair., Inst. Adv. Med. Sci., Hyogo Col. Med.

1-O-C2-417:0617:18 Amthamine, a selective histamine H₂ receptor agonist alleviates cerebrovascular damage after traumatic brain injury in mice Shotaro Michinaga, Kyomi Sonoda, Naoki Inazuki, Tomokazu Watano, Hiroyuki Mizuguchi Dept. pharmacol. Osaka-ohtani Univ.

Oral Sessions

Learning, Memory, Cognition (1)

1-O-C3-117:3017:42 Effects of high fat diet feeding and lipopolysaccharide treatment on neuroinflammation, neurogenesis, or cognitive function in mice Toshiaki Ishizuka¹, Wataru Nagata¹, Sayaka Takahashi¹, Hiroyuki Ohta¹, Yasushi Satoh² ¹Dept. Pharmacol., Natl. Def. Med. Coll., ²Dept. Biochem., Natl. Def. Med. Coll.

1-O-C3-217:4217:54 Recovery of memory deficits by the overexpression of Shati/Nat8l in the hippocampus in a mouse model of Alzheimer’s disease Chino Kakeru¹, Naotaka Izuo¹, Tomoharu Kuboyama², Chihiro Tohda², Shinichi Muramatsu^3,4, Atsumi Nitta¹ ¹Dept of Pharmaceutical and Neuropharmcol Therap, Fact of Pharmaceutical Sci, Grad Univ of Medical and Pharm Sci, Univ of Toyama, ²Sect of Neuromedical Sci, Div of Biosci, Inst of Nat Med, Univ of Toyama, ³Div of Neuro Gene Thera, Open Innov Ctr, Univ of Jichi Med, ⁴Ctr of Gene & Cell Thera, Ins of Med Sci, Univ of Tokyo

1-O-C3-317:5418:06 Coffee polyphenols prevent cognitive decline and suppress amyloid β plaques in APP/PS2 transgenic mouse Keiko Ishida, Masaki Yamamoto, Kensuke Misawa, Hitomi Nishimura, Koichi Misawa, Naoki Yamamoto, Noriyasu Ota Kao Corporation Biological Science Research

1-O-C3-418:0618:18 Coffee polyphenols ameliorate cognitive decline via maintenance of blood-brain barrier (BBB) integrity in senescence-accelerated mouse prone 8 (SAMP8) Nishimura Hitomi, Masaki Yamamoto, Keiko Ishida, Tomoya Hirata, Naoki Yamamoto, Kouichi Misawa, Takatoshi Murase, Noriyasu Ota Kao Corporation Biological Science Research

1-O-C3-518:1818:30 Chlorogenic acid (5-caffeoylquinic acid) suppresses cognitive decline by facilitating Aβ clearance in APP/PS2 transgenic mice Keiko Ishida, Masaki Yamamoto, Hitomi Nishimura, Tomoya Hirata, Koichi Misawa, Naoki Yamamoto, Noriyasu Ota Kao Corporation Biological Science Research