program｜The 94th Annual Meeting of the Japanese Pharmacological Society

Symposium16

Integrative understanding of cellular and tissue homeostasis maintained by stiffness remodeling

2-S16-19:0010:30 Role of stiffness sensors in skeletal muscle regeneration Yuji Hara¹, Kotaro Hirano¹, Yasuo Mori¹, Masato Umeda^1,2 ¹Grad. Sch. Eng., Kyoto Univ., ²HOLO BIO Co., Ltd

2-S16-29:0010:30 Identification of novel stiffness sensor GPCRs and functional analysis in muscular tissues. Akiyuki Nishimura^1,2, Kosuke Sakata³, Tomohiro Tanaka^1,2, Kazuhiro Nishiyama³, Yuri Kato³, Motohiro Nishida^1,2,3 ¹Div. Cardiocirc. Signal., NIPS, NINS, ²Cardiocirc. Dynamism, ExCELLS, ³Grad. Sch. Pharmaceut. Sci., Kyushu Univ.

2-S16-39:0010:30 The role of TRPV2 on physiological and pathological remodeling of myocytes Yuki Katanosaka Dept. Cardiovasc. Physiol. Okayama. Univ. Grad. Sch. Med.

2-S16-49:0010:30 In vivo motion detection of cells in the cochlear sensory epithelium for determining the stiffness. Fumiaki Nin¹, Takeru Ota², Samual Choi³, Hiroshi Hibino² ¹Dept. of Physiol. Gifu Univ. Grad. Sch. of Med., ²Dept. of Mol. Physiol. Niigata Univ. Schl. of Med., ³Dept. of Eng. Niigata Univ.

Symposium22

Dynamic regulation of robustness and homeostasis of cardiac function through inter-organ communication

2-S22-110:3012:00 Mechanism for maintaining homeostasis of cardiac function through cardio-renal interactions Yoshinori Mikami, Satomi Adachi-Akahane Dept. Physiol., Fac. Med., Toho Univ.

2-S22-210:3012:00 Cardiovascular regulation by brain renin-angiotensin system and inflammation Keisuke Shinohara Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu University

2-S22-310:3012:00 Treatment with brain-derived neurotrophic factor for skeletal muscle abnormalities in heart failure Shintaro Kinugawa Department of Experimental and Clinical Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu University

2-S22-410:3012:00 Gut-initiated intratissue-network in the development and control of diseases Jun Kunisawa NIBIOHN

YIA

Receptor, Channel, Transporter (2), Cell Death (1)

2-Y-E1-115:3015:42 Recombinant human α₂δ-1 purification for structural analysis of mirogabalin binding mode Daisuke Kozai^1,2, Nobutaka Numoto³, Kouki Nishikawa⁴, Akiko Kamegawa^4,5, Hiroyuki Hanzawa⁶, Kousei Shimada⁷, Mizuki Takahashi⁶, Yutaka Kitano⁷, Yoshinori Fujiyoshi^4,5 ¹CeSPI, Nagoya Univ., ²JBIC, ³Med. Res. Inst., Tokyo Med. and Dent. Univ., ⁴CeSPIA Inc., ⁵Adv. Res. Inst., Tokyo Med. and Dent. Univ., ⁶Daiichi-Sankyo RD Novare Co., Ltd., ⁷Daiichi-Sankyo Co., Ltd.

2-Y-E1-215:4215:54 V1a Vasopressin Receptor Deficient Mice as a Model for Accelerated Aging Casmad Fujianti, Morio Azuma, Sajjaviriya Chortip, Hiroyoshi Tsuchiya, Taka-aki Koshimizu Juchi Med. Univ. Mol. Pharmacol.

2-Y-E1-315:5416:06 1,2-Naphthoquinone functions as an activator of the EGF receptor via covalent modification of a specific lysine residue Kengo Nakahara¹, Tomoki Tsuchida¹, Yumi Abiko², Yoshito Kumagai², Takashi Uehara¹ ¹Department of Medical pharmacology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, ²Environmental Biology Laboratory, Faculty of Medicine, University of Tsukuba

2-Y-E1-416:0616:18 EGFP-tagged Syntaxin 17 localized on autophagosome is accumulated by Doxorubicin Guanjie Li¹, Delan Lin¹, Noriko Toda^1,2, Masaki Saito¹, Masanori Yamauchi², Kazuhiko Yanai^1,3, Takeya Sato¹ ¹Dept. Mol. Pharmacol., Tohoku Univ., Grad. Sch. Med, ²Dept. Anes & Perio Med., Tohoku Univ., Grad. Sch. Med, ³Dept. Pharmacol., Tohoku Univ., Grad. Sch. Med

YIA

ER stress, Functional Peptide, Toxicopharmacology (1)

2-Y-E2-116:3016:42 Transcription factor ATF4 maintains pancreatic β-cell identity during ER stress Keisuke Kitakaze^1,2, Miho Oyadomari¹, Jun Zhang¹, Yoshimasa Hamada¹, Yasuhiro Takenouchi², Kazuhito Tsuboi², Yoshio Fujitani³, Yasuo Okamoto², Seiichi Oyadomari¹ ¹Div. of Mol. Biol., Inst. for Genome Res., Inst. of Adv. Med. Sci., Tokushima Univ., ²Dept. of Pharmacol., Kawasaki Med. Sch., ³Lab. of Dev. Biol. and Metab. Inst. for Mol. and Cell. Regul., Gunma Univ.

2-Y-E2-216:4216:54 Role of alpha 1 antitrypsin-induced ER stress in placental trophoblast cells Kanoko Yoshida¹, Kazuya Kusama¹, Kiyoko Kato², Gen Ishikawa³, Mikihiro Yoshie¹, Kazuhiro Tamura¹ ¹Dept. Pharmacol., Tokyo Univ. Pharm. & Life Sci., ²Dept. Obstet. & Gynecol., Kyushu Univ., ³Dept. Obstet. & Gynecol., Nippon Med. Sch.

2-Y-E2-316:5417:06 Globin Digest Exerts Anti-Obesity Effects through UCP1 Upregulation in Zebrafish and Mouse Obesity Models Zang Liqing¹, Yasuhito Shimada², Hiroko Nakayama¹, Izumi Matsuoka¹, Youngil Kim³, Djong-Chi Chu³, Lekh Raj Juneja³, Rika Tsuruta⁴, Yuka Sasakawa⁴, Junya Kuroyanagi⁵, Norihiro Nishimura¹ ¹Grad. Sch. of Regional Innovation Studies, Mie Univ., ²Dept. Integr. Pharmacol., ³Rohto Pharmaceut. Co., Ltd., ⁴MG Pharma Inc., ⁵UMOU Sci. Lab

2-Y-E2-417:0617:18 Comprehensive cardiotoxicity assessment of hydroxychloroquine using human iPSC-derived cardiomyocytes Yanagida Shota^1,2, Ayano Satsuka¹, Sayo Hayashi¹, Atsushi Ono², Yasunari Kanda¹ ¹Div. Pharmacol, NIHS, ²Div. Pharmaceut. Sci, Grad Sch Med., Dent. and Pharmacet. Sci, Okayama Univ.

YIA

Hypertension (2), Vascular Endothelium

2-Y-E3-117:3017:42 Chemerin/CMKLR1 in the brain of spontaneously hypertensive rats mediates systemic hypertension Atsunori Yamamoto¹, Naoko Yamaguchi², Shoshiro Okada², Kosuke Otani¹, Muneyoshi Okada¹, Hideyuki Yamawaki¹ ¹Lab. Vet Pharmacol., Sch., Vet. Med., Kitasato Univ., ²Dept. Pharmacol., Sch., Med., Aichi Med. Univ.

2-Y-E3-217:4217:54 The alteration of molecular properties in plasma extracellular vesicles from spontaneously hypertensive rats Kosuke Otani, Muneyoshi Okada, Hideyuki Yamawaki Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Kitasato University

2-Y-E3-317:5418:06 Evaluation of the pathological symptoms in retinal vascular disease with neovascular glaucoma Anri Nishinaka, Miruto Tanaka, Koki Nitta, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara Gifu Pharmaceut . Univ.

2-Y-E3-418:0618:18 The role of ANKFY1 in endothelial cells for retinal angiogenesis Miruto Tanaka¹, Shinsuke Nakamura¹, Masashi Maekawa^2,3, Shigeki Higashiyama^2,3, Hideaki Hara¹ ¹Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, ²Division of Cell Growth and Tumor Regulation, Proteo-Science Center, Ehime University, ³Department of Biochemistry and Molecular Genetics, Ehime University Graduate School of Medicine