The 93rd Annual Meeting of the Japanese Pharmacological Society

March 18 (Wed) Room D

Symposium29
Recent advances towards pharmacological and toxicological applications of human induced pluripotent stem cells.
3-S29-18:3010:00
Current status and future perspectives in cardiovascular and neural toxicity testing using human iPSC technology
Yasunari Kanda
Div Pharmacol, NIHS
3-S29-28:3010:00
Analysis of contractile functions of human iPS-derived cardiomyocytes using motion field imaging
Junko Kurokawa, Kazuho Sakamoto, Masahiko Yamaguchi
Dept. Bio-Info. Pharmacol., Univ. Shizuoka
3-S29-38:3010:00
High throughput screening in silico via computer models of induced-pluripotent stem cell derived cardiomyocytes
Colleen Clancy1
1Dept. of Physiology and Membrane Biology, 2Dept. of Physiology, 3School of Medicine
3-S29-48:3010:00
Personalized medicine diagnostics for cardiac safety
Ksenia Blinova
US FDA, CDRH/OSEL/DBP iPSC&EP lab
3-S29-58:3010:00
Modeling of psychiatric disorders using iPSC technology
Takanobu Nakazawa1,2, Ryota Hashimoto3,4, Kazuhiro Takuma1,5, Hitoshi Hashimoto2,5,6,7,8
1Dept Pharmacol, Grad Sch Dentistry, Osaka Univ, 2Lab Mol Neuropharmacol, Grad Sch Pharmaceut Sci, Osaka Univ., 3Dept Pathol Mental Dis, Natl Inst Mental Health, Natl Ctr Neurol Psychiatry, 4Osaka Univ., 5Mol Res Ctr Children’s Mental Dev, United Grad Sch Child Dev, Osaka Univ., 6Inst Datability Sci, Osaka Univ., 7Inst Open Transdiscip Res Initiatives, Osaka Univ., 8Dept Mol Pharmaceut Sci, Grad Sch Med, Osaka Univ.
Symposium32
Frontiers in cancer therapy
3-S32-110:0011:30
Development of antibody-drug conjugates that target vascular endothelial cells to promote anti-tumor activity
Shangze Gao, Masahiro Nishibori
Dept. Pharm., Grad. sch. Med. Dent.Pharmaceutic., Okayama Univ.
3-S32-210:0011:30
S100A8/A9 and its novel receptors play a critical part in organ tropic cancer metastasis
Masakiyo Sakaguchi
Dept Cell Biol, Okayama Univ Grad Sch Med, Dent, Pharm Sci
3-S32-310:0011:30
Development of anti-cancer agent targeting on (pro)renin receptor
Akira Nishiyama, Asadur Rahman
Dep. Pharmacology, Kagawa Med. School
Oral Sessions
3-O-10813:5014:02
Involvement of intracellular Fe2+ against oxidative stress in CRR cells
Kazuo Tomita1,2, Yoshikazu Kuwahara1,3, Kento Igarashi1,2, Yuko Takashi1,4, Taisuke Nagasawa1, Sayuri Yamanishi1,5, Koh-Ichi Tanaka1,2,6, Jyun-Ichi Kitanaka6, Nobue Kitanaka6, Akihiro Kurimasa3, Miyawaki Shou-Ich5, Yoshihiro Nishitani4, Nobuyoshi Nishiyama4, Motohiko Takemura5, Manabu Fukumoto7, Tomoaki Sato1
1Dept. Applied Pharm., Grad. Sch. Med. & Dent. Sci., Kagoshima Univ., 2Div. Pharmacol., Dept. Pharm., Sch. Pharm., Hyogo Univ. Health Sci., 3Dept. Radiation Biol. Med., Facul. Med, Tohoku Med. Pharm. Univ., 4Dept. Restorative Dentistry and Endodontology, Grad. Sch. Med. & Dent. Sci., Kagoshima Univ., 5Dept. Orthodontics and Dentofacial Orthopedics, Grad. Sch. Med. & Dent. Sci., Kagoshima Univ., 6Dept. Pharmacol., Hyogo Col. Med., 7RIKEN, AIP
3-O-10914:0214:14
Anti-leukemia activity of baicalin and baicalein, flavonoids derived from Scutellaria baicalensis Georgi
Takeaki Nitto, Takumi Sugimoto, Kohei Sawaki
Lab. Pharmacotherapy, Yokohama Univ. Pharm.
3-O-11014:1414:26
Baicalein disturbs the morphological plasticity and motility of breast adenocarcinoma cells depending on the tumour microenvironment.
Takeshi Teranayashi1, Katsuhiro Handa2, Takahiro Akamine1, Toshimasa Ishizaki1
1Dept. Pharm., Oita Univ., 2Clin. Eng. Res. Cent., Oita Univ.
3-O-11114:2614:38
An anti-CD133 monoclonal antibody CMab-43 exerts anti-tumor and anti-metastasis activities for colon cancers
Yukinari Kato1, Mika Kaneko1, Tomokazu Ohishi2, Manabu Kawada2
1Dept. Antibody Drug Development, Tohoku Univ. Grad. Sch. Med., 2BIKAKEN, Numazu
3-O-11214:3814:50
Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma
Akira Nishiyama, Yuki Shibayama, Asadur Rahman
Dept. Pharmacol. Kagawa Univ. Med. School
Oral Sessions
3-O-11914:5015:02
Influence of Anticancer Agent on Erectile Function; Vincristine Caused Erectile dysfunction Through Endothelial Dysfunction and Injury to the Cavernous Nerve in Rats
Tomoya Kataoka1, Jun Suzuki2, Akimasa Sanagawa3, Yuji Hotta2, Yasuhiro Maeda4, Kazunori Kimura1,2,3
1Dept. Clinical Pharmacieutics, Grad. Sch. Med., Nagoya City Univ., 2Dept. Hospital Pharmacy, Grad. Sch. Pharm., Nagoya City Univ., 3Dept.Pharmacy, Nagoya City Univ. Hospital, 4Dept. Reserch Promotion and Support Headqarters, Fujita Health Univ.
3-O-12015:0215:14
Patient-Derived Cancer Xenograft Xebrafish Model (PDXZ) and Personalized Medicine
Kayoko Yamada1,3, Itsuko Kuroda1,3, Riho Masukawa1,3, Yuka Mizutani1,3, Aoi Hayasaki2, Yasuhiro Murata2, Naohisa Kuriyama2, Masanori Kishiwada2, Shuji Isaji2, Toshio Tanaka1,3
1Dept. Systems Pharm., Grad. Sch. Med., Mie Univ., 2Dept. Heptobil. Pacreat.Transplant. Surg. Grad. Sch. Med. Mie Univ., 3Mie Univ. Medical Zebrafish Research Center
3-O-12115:1415:26
Chronic exposure to hypoxia facilitates chemotherapy sensitivity with downregulation of MDR1.
Licht Miyamoto1, Yuko Yagi1, Aya Hatano1, Yasumasa Ikeda2, Shinji Abe3, Toshiaki Tamaki2, Koichiro Tsuchiya1
1Dept. Medical Pharmacology, Inst. of Biomedical Sciences, Tokushima Univ., 2Dept. Pharmacology, Inst. of Biomedical Sciences, Tokushima Univ., 3Dept. Clinical Pharmacy Practice Pedagogy, Inst. of Biomedical Sciences, Tokushima Univ.
3-O-12215:2615:38
Establishment of orthotopic transplantation model of mouse gallbladder cancer organoid for development and efficacy evaluation of anti-tumor agents.
Kato Shingo1, Tetsuya Matsuura2, Daisuke Kurotaki3, Yoshitaka Hippo4, Tomohiko Tamura3, Atsushi Nakajima2
1Dept. Clinical Cancer Genomics, Yokohama City University Hospital, 2Dept. Gastroenterology and Hepatology, Grad. Sch. Med., Yokohama Univ., 3Dept. Immunology., Grad. Sch. Med., Yokohama Univ., 4Division of Molecular Carcinogenesis, Chiba Cancer Center Research Institute
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