The 93rd Annual Meeting of the Japanese Pharmacological Society

March 17 (Tue) Room I

Symposium22
Novel therapeutic strategies for the fibrosis of circulatory diseases
2-S22-18:5010:20
Doxorubicin induces trans-differentiation in cardiac fibroblasts via cell death-independent pathways
Masanari Umemura1,2, Ryo Tanaka1,2, Masatoshi Narikawa2, Rina Nakakaji1,3, Islam Rafikul1, Kohei Osawa1,3, Mayu Hikichi1, Yoshihiro Ishikawa1
1Dept. CVRI., Grad. Scho. Med. Yokohama Univ., 2Medical Science and Cardiorenal Medicine., Grad. Scho. Med. Yokohama Univ., 3Dept. Oral and Maxillofacial Surgery., Grad. Scho. Med. Yokohama Univ.
2-S22-28:5010:20
The roles of gap junctional intercellular communication in non-alcoholic steatohepatitis (NASH) and liver fibrosis
Aya Naiki-Ito
Dept. Exp. Pathol. Tumor Biol., Nagoya City Univ. Grad. Sch. Med. Sci.
2-S22-38:5010:20
exploring mechanisms of renal fibrosis progression
Daisuke Nakano
Dept. Pharmacol., Kagawa Univ.
2-S22-48:5010:20
Vascular remodeling in pulmonary arterial hypertension: roles of CaSR and PDGF
Aya Yamamura
Dept. Physiol., Aichi Med. Univ.
Symposium26
Chronic inflammation – novel mechanism and drug development
2-S26-110:2011:50
Coordinated regulation of lipid metabolism and inflammatory response in macrophages
Yumiko Oishi
Dept. of biochemistry and molecular biology, Nippon Medical School
2-S26-210:2011:50
Immuneregulation and tissue repair by Ym1+ monocytes
Kenichi Asano1, Kenta Kikuchi1, Naoki Ikeda2, Masato Tanaka1
1Lab. of Immue Regulation, Tokyo Univ. Pharm. & Life Sci., 2Hokkaido Univ.
2-S26-310:2011:50
Cross-talking between EMT and inflammatory responses
Noritaka Yamaguchi1,2, Naoto Yamaguchi2, Hiroyuki Takano1
1Dept. Mol. Cardiovasc. Pharmcol., Grad. Sch. Pharm. Sci., Chiba Univ., 2Lab. Mol. Cell Biol., Grad. Sch. Pharm. Sci., Chiba. Univ.
2-S26-410:2011:50
Systemic environment regulates central nervous system regeneration
Rieko Muramatsu
Dept. Mol. Neurosci., Nat. Inst. Neurosci., NCNP
YIA
organelle, signaling
Chair：Naoki Watanabe（Dept. Pharmacol., Kyoto Univ. Grad. Sch. Med.）
Chair：Koichiro Ozawa（Hiroshima Univ., Grad. Sch. Biomed & Health Sci., Depot. Pharmacother.）
2-YIA-4716:2016:32
Regulatory Mechanisms of Primary Ciliary Resorption and Cell Cycle Progression by a Dynein Light Chain, Tctex-1
Sara Ebrahimiazar, Kensuke Sakaji, Takeya Sato, Masaki Saito
Dept. Mol. Pharmacol., Tohoku Univ. Grad. Sch. Med.
2-YIA-4816:3216:44
Identification of a chemical chaperone for preventing protein aggregation and proteotoxicity under endoplasmic reticulum stress
Keisuke Kitakaze1,2, Shusuke Taniuchi1, Eri Kawano1, Yoshimasa Hamada1, Masato Miyake1, Miho Oyadomari1, Hirotatsu Kojima3, Hidetaka Kosako4, Tomoko Kuribara5, Suguru Yoshida5, Takamitsu Hosoya5, Seiichi Oyadomari1
1Div. of Mol. Biol., Inst. of Adv. Med. Sci., Tokushima Univ., 2Dept. of Pharmacol., Kawasaki Med. Sch., 3DDI, The Univ. of Tokyo, 4Fujii Memorial Inst. of Med. Sci., Inst. of Adv. Med. Sci., Tokushima Univ., 5Lab. of Chem. Biosci., Inst. of Biomater. and Bioeng., TMDU
2-YIA-4916:4416:56
Lysosomal Regulation of mTOR-AKT Signaling via the Vacuolar-type H+- ATPase
Hirofumi Morihara, Kiichiro Tomoda, Michio Asahi
Department of Pharmacology, Faculty of Medicine, Osaka Medical College
2-YIA-5016:5617:08
ATP increases ciliary beat frequency in mouse airway cilia through P2Y1 receptor
Tomoki Sekiya, Shingo Matsuyama, Yoichiro Isohama
Lab. Appl. Pharmacol. , Facul. of Pharm. Sci. , Tokyo Univ. of Sci.
Oral Sessions
fibrosis
Chair：Kota Saito（Dept. Biol. Informatics & Exp. Therap., Grad. Sch. Med., Akita Univ.）
Chair：Masato Katsuyama（Radioisotope Ctr., Kyoto Pref. Univ. Med.）
2-O-07017:2517:37
Phosphodiesterase 4 inhibitor and phosphodiesterase 5 inhibitor combination therapy has antifibrotic and anti-inflammatory effects in mdx mice with Duchenne muscular dystrophy
Yasunori Nio, Masayuki Tanaka, Yoshihiko Hirozane, Yo Muraki, Takanori Matsuo, Mitsugi Ookawara, Masatoshi Hazama
Takeda pharmaceutical company
2-O-07117:3717:49
Inhibition of transcription factor OASIS attenuated kidney fibrosis
Ayaha Yamamoto1, Masanori Obana1, Takafumi Nakae1, Yoshiaki Miyake1, Sayuri Mitsuoka1, Makiko Maeda2, Kazunori Imaizumi3, Kotaro Matsumoto1, Yasushi Fujio1
1Laboratory of Clinical Science and Biomedicine, Grad. Sch. Pharm., Osaka Univ., 2Education and Research Project for Pharm.D, Grad. Sch. Pharm., Osaka Univ., 3Department of Biochemistry, Grad. Sch. Biomed. & Health Sci., Hiroshima Univ.
2-O-07217:4918:01
Reversal of myofibroblast phenotype due to the adhesion of Lung mixed culture-derived epithelial cells (LMDEC)
Shuichi Matsuda1,2, Keita Ugai1, Hideki Mikami1,2, Masaki Suga1,2, Koichiro Tatsumi2, Masahiko Hatano1, Yoshitoshi Kasuya1,3
1Dept. Biomed. Sci., Grad. Sch. Med., Chiba Univ., 2Dept. Respirology, Grad. Sch. Med., Chiba Univ., 3Dept. Biochem. and Mol. Pharmacol., Grad. Sch. Med., Chiba Univ.
2-O-07318:0118:13
Ferric chloride induces irreversible pulmonary fibrosis in mice
Hidekideki Mikami1,3, Jundai Kim4, Shuichi Matsuda1,3, Keita Ugai1, Kento Yoshioka5, Masahiko Hatano2, Akiyoshi Fukamizu4, Koichiro Tatsumi3, Yoshitoshi Kasuya1
1Department of Biochemistry and Molecular Pharmacology, 2Department of Biomedical Science, 3Department of Respirology, Graduate School of medicine, 4Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), 5Departments of Pharmacology
2-O-07418:1318:25
Dissecting the role of CNOT6L deadenylase in pressure overload-induced cardiac fibrosis
Tomokazu Yamaguchi1, Teruki Sato1,2, Takafumi Minato1, Jianbo An1, Midori Hoshizaki3, Hiroyuki Watanabe2, Yumiko Imai3, Tadashi Yamamoto4, Keiji Kuba1
1Dept. of Biochem. and Metab. Sci., Akita Univ. Grad. Sch. of Med., 2Dept. of Cardiovasc. Med., Akita Univ. Grad. Sch. of Med., 3NIBIOHN, 4OIST
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