program｜The 93rd Annual Meeting of the Japanese Pharmacological Society

Morning Seminar2

Viral vectors for manipulation and recording of neural activity

2-MS28:208:50 Viral vectors for manipulation and recording of neural activity Kazuki Nagayasu Dept. Mol. Pharmacol., Grad. Sch. Pharm. Sci, Kyoto Univ.

Symposium20

The ideal pain control -Novel findings making a breakthrough in opioid analgesics-

2-S20-18:5010:20 Current status and issues in clinical use of opioids: expectations for development of novel analgesics Takayuki Nakagawa Dept. Clin. Pharmacol. Ther., Kyoto Univ. Hosp.

2-S20-28:5010:20 Further classification of μ-opioid analgesics based on “intracellular biased-signaling through μ-opioid receptors” Naoko Kuzumaki, Minoru Narita Dept. Pharmacol., Hoshi Univ.

2-S20-38:5010:20 MOPr-DOPr heteromer: The meaning and possibility as novel therapeutic target for pain control Wakako Fujita¹, Lakshmi Devi² ¹Dept. Frontier Life Sci., Grad. Sch. Biomed. Sci., Nagasaki Univ., ²Dept. Pharmacol., Icahn Sch. Med. Mt. Sinai

2-S20-48:5010:20 Safe opioid analgesics targeting nociceptin receptor in primates Norikazu Kiguchi¹, Mei-Chuan Ko² ¹Dept. Pharmacol., Wakayama Med. Univ., ²Dept. Physiol. Pharmacol., Wake Forest Univ. Sch. Med.

YIA

2-YIA-3010:3510:47 Zinc-aggravated M1 microglia suppress astrocytic engulfing activity via P2X7 receptors Takaaki Aratake^1,2, Youichirou Higashi¹, Tomoya Hamada¹, Takahiro Shimizu¹, Shogo Shimizu¹, Suo Zou¹, Masaki Yamamoto¹, Yoshiki Nagao¹, Rina Nakamura¹, Toshifumi Akizawa¹, Motoaki Saito¹ ¹Dept. of Pharmacol., Kochi Med. Sci., Kochi Univ., ²JSPS Research Fellow

2-YIA-3110:4710:59 A new mechanism for somatosensory information processing by descending noradrenergic pathway via spinal dorsal horn astrocytes Kohei Yoshihara¹, Yuta Kohro¹, Tsuyoshi Matsuda¹, Hidetoshi Tozaki-Saitoh¹, Kazuhide Inoue², Makoto Tsuda¹ ¹Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, ²Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University

2-YIA-3210:5911:11 Involvement of glymphatic system in amyotrophic lateral sclerosis pathology Hirose Mikako¹, Mito Asano¹, Shusei Shitara¹, Yoichiro Abe², Masato Yasui², Eiichi Tokuda³, Yoshiaki Furukawa⁴, Hidemi Misawa¹ ¹Div Pharmacol, Fac Pharm, Keio Univ, ²Div Pharmacol, Fac Med, Keio Univ, ³Phac Pharm, Nihon Univ, ⁴Div Chem, Fac Sci Tech, Keio Univ

2-YIA-3311:1111:23 Anti-HMGB1 mAb therapy for intracerebral and subdural hemorrhage in rats Dengli Wang¹, Keyue Liu¹, Hidenori Wake¹, Kiyoshi Teshigawara¹, Shuji Mori², Masahiro Nishibori¹ ¹Dept. Pharm., Grad. Sch. Med., Okayama Univ., ²Sch. Pharm., Shujitsu Univ

2-YIA-3411:2311:35 Aquaporin-4 facilitates paravascular space closure and neuronal activity reduction after water intoxication Tomoe Ishikawa¹, Miyuki Unekawa², Yutaka Tomita², Jin Nakahara², Masato Yasui¹ ¹Department of Pharmacology School of Medicine, Keio University, ²Department of Neurology School of Medicine, Keio University

Symposium24

Neuroimmune crosstalk and pain

2-S24-116:1517:45 Regulation of pain signaling by the innate immune system Junting Huang, Maria A. Gandini, Said M’dahoma, Daniel A. Muruve, Gerald W Zamponi Cumming School of Medicine, University of Calgary

2-S24-216:1517:45 The role of meningeal mast cells in ATP-induced nociceptive firing in trigeminal afferents. Anti-nociceptive effects of hydrogen sulfide Guzel Sitdikova¹, Ksenia Koroleva¹, Elizaveta Ermakova¹, Alsu Mustafina¹, Rashid Giniatullin^1,2 ¹Dept of Human and Anim Physiol, Inst of Fundamental Med and Biol, Kazan Federal Univ, Kazan, Russia, ²A. I. Virtanen Inst for Mol Sci, Univ of Eastern Finland, Kuopio, Finland

2-S24-316:1517:45 Brain-immune system and its maintenance of brain pain memory in fibromyalgia Hiroshi Ueda, Naoki Dozono, Keigo Tanaka Dept. Mol Pharmacol,, Grad. Sch. Pharmac., Kyoto Univ

2-S24-416:1517:45 Neuroimmune crosstalk in neuropathic and visceral pain: HMGB1 and ATP as key mediators Atsufumi Kawabata Lab. Pharmacol. Pathophysiol., Fac. Pharm., Kindai Univ.

Oral Sessions

2-O-05717:4517:57 The production trial of high HPRT activity - low XOR activity - Uox knockout mice Makoto Hosoyamada¹, Naoko Tomioka H¹, Toshio Ohtsubo² ¹Dept. Human Physiol. Pathol., Fac. Pharma-Sci., Teikyo Univ., ²Fukuoka Red Cross Hosp.

2-O-05817:5718:09 Involvement of Vanin-1 in Renal Proximal Tubular Injury in Dahl-Salt Sensitive Rats Keiko Hosohata¹, Denan Jin², Shinji Takai², Kazunori Iwanaga¹ ¹Education and Research Center for Clinical Pharmacy, Osaka University of Pharmaceutical Sciences, ²Department of Innovative Medicine, Osaka Medical College

2-O-05918:0918:21 Modulistat, a PHD inhibitor, ameliorated erythropoiesis in adenine-induced nephropathy mice Daisuke Nakano, Li Lei, Akira Nishiyama Dept. Pharmacol., Kagawa Univ.

2-O-06018:2118:33 The involvement of ferroptosis on cisplatin-induced nephrotoxicity Yasumasa Ikeda¹, Hirofumi Hamano², Yuya Horinouchi¹, Mitsuhiro Goda², Yoshito Zamami², Licht Miyamoto³, Keisuke Ishizawa², Koichiro Tsuchiya³ ¹Dept. Pharm., Tokushima Univ. Grad. Sch., ²Dept. Clin Pharm., Tokushima Univ. Grad. Sch., ³Dept. Med. Pharm., Tokushima Univ. Grad. Sch.