In this project, various imaging technologies will be developed to visualize the complicated life systems by integrating multiple disciplines such as physics, chemistry, biology, information science, and computational science. The trans-scale-scope, one of the core facilities, is equipped with the ability to capture single-shot images of more than millions of cells at microscopic spatial resolution, allowing to investigate the emergence mechanism of each cell or individuals characteristics, that cannot be achieved by conventional technologies. This technology leads to a deeper understanding of the principle of life. Across the world, there are large-scale projects such as the Francis Crick Institute (UK) that was established with a capital of 100 billion yen and an annual budget of 17 billion yen. It is of vital importance to develop and share an unrivaled measurement equipment that can contribute to a broad range of research across the globe. This project is expected to contribute to all aspects of medical applications, such as personalized medicine, precision predictive medicine, and to solving problems directly related to human health and welfare, and the safety and security of the people. In this symposium, the latest research results related to this idea are introduced, and future problems and prospects are discussed.