To be health, it is important to adapt to society in which everything communicates with each other. However, the mechanism of social adaptation is poorly understood due to the lack of established methodologies that control intra-individual communication. To solve this problem, we have developed the hexagonal columnar animal cage that can control communication within individual mice by using removal partitions. In the experiment, male ICR-, ddY- BALB/c-, and C57BL/6J-strains of mice were used to evaluate the relationship between contact conditions and depression in tail suspension test. In the group in which only three mice of the same strain were contacted, the depression level of ICR mice was not different even when the contact conditions were changed. The depression levels of ddY mice were exacerbated when separated from each other by using partitions with or without punched holes. The depression levels of BALB/c mice were exacerbated only when isolated by using partitions without punched holes. On the other hand, the partition with punched holes reduced the depression levels in C57BL/6J mice. These results indicate that means of stress-inducible social communication is different between mice strain. Our hexagonal columnar animal cage revealed that there are diverse communication styles for adapting to society.