In the case of pharmacotherapy, we believe that the nurse need to acquire knowledge and skill about the safety management of drugs, to prevent the occurrence of harmful effect of drugs in the current medical care. In response to the voices of the victim of harmful effect of drugs in Japan, Ministry of Education, Culture, Sports, Science and Technology have surveyed since 2010 on the education to attain the extermination of the harmful side effect induced by unsuitable using drugs in each school of medicine, dentistry, pharmacy, and nursing. In this study, we analyzed current status and issues of pharmacology education in the education of nursing, from the viewpoint of the education for harmful effect of drugs. In addition, we examined what is the requirement as a nurse to check and prevent the harmful side effect induced by unsuitable using drugs if we could find the suitable education method of harmful effect of drugs because a school hour was tight and limited on the school of nursing. We carried out this study with the approval of the Saitama Prefectural University Ethical Review Board (28095). As a result, 76% of students who obtained informed consent could explain or know thalidomide incident. Only 34% of students could understand the difference between harmful effect and drug abuse, until they took a pharmacology class. On the other hand, it became clear that 84% of students thought that it was possible to prevent or relieve harmful effect of drugs as a nurse.